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Infectious diseases > Herpes > Flashcards

Herpes Flashcards

1
Q

What do HHV1/2 cause?

A

HSV
Oral/genital ulcers - painful
HSV-1: encephalitis
Neonatal herpes infection

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2
Q

What is the treatment of HHV1/2?

A

Oral acyclovir

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3
Q

What is HHV3?

A

VZV
Chickenpox/shingles
Ramsay hunt syndrome
Congenital varicella syndrome

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4
Q

How does HHV3 present?

A

dermatomal regions

vesicles/ulcers

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5
Q

What is the treatment of normal chickenpox?

A

Calamine lotion
Supportive
school exclusion - INFECTIOUS UNTIL LESIONS ARE DRY AND CRUSTED OVER (~5 days)

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6
Q

When does chickenpox require more serious treatment and with what

A

when immunocompromised or newborns w peripartum exposure

Rx: VZ Igs the IV aciclovir

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7
Q

Describe the rash in chicken pox

A

starts on head/trunk then spreads

macular->papular->vesicular

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8
Q

How is chickenpox spread

A

resp

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9
Q

What is HHV4? What does it cause?

A 
EBV
Causes:
Glandular fever 
Burkitt's lymphoma 
Oral hair leukoplakia 
PTLD
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10
Q

What is the treatment of EBV ?

A

ganciclovir

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11
Q

How does glandular fever present?

A

Sore throat
Pyrexia
Lymphadenopathy

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12
Q

What happens when someone with glandular fever takes ampicillin/amoxicillin?

A

maculopapular, pruritic rash

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13
Q

How is glandular fever diagnosed?

A

FBC and monospot test - heterophil ab test

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14
Q

What is the management of glandular fever?

A

supportive - rest, simpel analgesia

avoid playing contact sports for 8 weeks after having it to reduce the risk of splenic rupture

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15
Q

What is HHV 5? How can it present?

A

CMV
Congenital CMV
CMV mononucleosis
CMV retinitis (HIV)

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16
Q

What is the features of congenital CMV?

A 
growth retardation 
microcephaly 
sensorineural deafness
encephalitis
hepatosplenomegaly
pinpoint petechial blueberry muffin lesions
17
Q

What are the histological features of someone with CMV?

A

owls eye appearance on inclusion bodies

18
Q

How does CMV retinas present? how does it present on fundoscopy?what is rx

A

blurred vision
retinal haemorrhages and necrosis
rx: IV ganciclovir

19
Q

What is HHV 6?

A

roseola infantum

20
Q

What is HHV 8?

A

Kaposi sarcoma

21
Q

What is the rx of HHV 8?

A

Tocilizumab
ART
Cryotherapy

Infectious diseases (8 decks)

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