HERP Flashcards
not associated with HIV. young african males. also in immunocompromised. AGRESSIVE
Two further types. One is aggressive in children <10. Other is in men 20-50 and nodular/infiltrative.
KSHV
endemic kaposi sarcoma
adulthood and childhood forms. highly contagious
itchy rash that spreads downwards. primary infection mild and symptomatic. adult version is dependent on dermatome carrying virus
secondary viral infection, viral pneumonia. encephalitis. postherpetic neuralgia
VACCINIATION. diagnose clinical presentation
VZV
AGGRESSIVE. Skin, face, gastrointestinal, urogenital, resp tract. MSM. In Africa it is heterosexual HIV patients
KSHV
epidemic related kaposi sarcoma
M=F. more common in adolescents. KISSING DISEASE. can also spread through semen, blood and organ transfusions.
infectious mononucleosis. hairy leukoplakia. can reactivate with stress/anxiety.
splenomegaly. potential rupture risk
EBV
<3 and 3-5
transmission saliva.
roseola infantum
infantile seizures [if no rash]. meningitits. IM in adults.
diagnose serology. no vaccine
HHV-6/HHV-7
antiviral drugs
valaciclovir
acyclovir
famiciclovir
F>M . dependent on sexual habits; spread through contact. genital infection
can be recurrent. HSV-encephalitis.
diagnose through swab. DN detection. PCR to differentiate
hsv-2
<6 and YA. spread through oral, sex, urine, blood, breast milk.
mostly no signs. otherwise infectious mononucleosis.
diagnose PCR, serology etc.
HCMV
<5 YEARS
mainly spread oral. also shedding virus from skin. oral secretions. orofacial lesions that ulcerate
recurrence through autoinnoculation - herpretic whitlow / keratitis / encephalitis
diagnose through swab. DN detection. PCR to differentiate
HSV-1
less aggressive. Lymphadenopathy and visceral involvement. Seen in organ transplant patients. IMMUNOCOMPROMISED
can turn into KS here.
KSHV
latrogenic kaposi sarcoma
does not cause worldwide infection.
middle-aged or older men of mediterranean, eastern European and middle eastern heritage without HIV infection. Involves skin, limbs and is slow developing. DOES NOT INVOLVE LYMPH NODES
KSHV
Classical kaposi sarcoma