Herbals Flashcards

1
Q
  • Herbals that Prolong Anesthesia Effect - Kava Kava:
  • Concerns
  • Potential to increase ___ of anesthetics
  • Potential for addiction, tolerance, and withdrawl after abstinence
  • Side effects: headache, dizziness, loss of coordination, sluggish reflexes, and GI discomfort.
  • Long-term use may cause ___ and ___, photosensitivity, ___
A

sedative effects
dry scaly skin and yellow discoloration of skin and nails
hepatotoxicity

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2
Q

*Herbals that Prolong Anesthetic Effect:

Sedative, mild anxiolytic, sleep aide?

  • Potential to ___ of anesthesia; should be avoided with ???
  • Side effects: headache, excitability, ataxia, and GI discomfort
  • Can develop? and will see ??
A

Valerian

  • potentiate sedative effect
  • barbiturate, opioids, benzodiazepine
  • withdrawal syndrome
  • Delirium
  • Cardiac abnormalities
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3
Q

*Herbals that Prolong Anesthetic Effect

  • “Prozac alternative”
  • Used to treat depression
A

St. Johns Wort

Hypericum perforatum

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4
Q

___ = Side effects: allergic reactions, headache, dizziness, restlessness, fatigue, GI upset and *photosensitivity, and additive effects with anesthesia

A

St. Johns Wort

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5
Q

St. Johns Wort

  • Cautions if patient taking prescription ___ (may lead to ?)
  • Induction of ___
A

MAO inhibitors
syndrome of central serotonin excess
cytoochrome P450 complex in the liver

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6
Q

*Herbals that prolong Anesthetic Effect:

Polynesian plant
CNS depressant, sedative, and anxiolytic

A

Kava kava

piper methysticum

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7
Q
  • Increased metabolism of drugs that use CP450 system and therefore reducing effectiveness of these drugs
  • Caution with: Indinovir (HIV), cyclosporines, digitalis, calcium channel blockers, beta blockers, phenobarb, phenytoin, birth control pills, benzodiazipines, coumadin, alfentanil, lidocaine, steroids, and non-steriodal anti-inflammatory drugs
A

St. Johns Wort

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8
Q

*Increased Risk of Bleeding

  • Used to improve cognitive function and improve circulation
  • Inhibition of ??
A

Gingko (gingko biloba)

platelet aggregation and platelet-activating factor (PAF)

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9
Q
  • Gingko
  • Side effects: headache, dizziness, GI upset, and ___
  • Potential to increase ___, especially when used with other medications that inhibit platelet aggregation
  • Enhances ___ of anticoagulants (coumadin, NSAIDs and ASA)
A
  • dermal sensitivity
  • risk of bleeding
  • anticoagulant effect
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10
Q

*Increase Risk of Bleeding

-Used to treat hypertension and lower cholesterol?
……..May have anticancer properties
~Inhibition of ___ and ___

A

Garlic (Allium Sativum)

~platelet aggregation and increased fibrinolysis

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11
Q
*Garlic 
Concerns:
-Potential to increase \_\_\_, especially when combined with other medications that \_\_\_
-Enhances \_\_\_
-\_\_\_\_
A
  • risk of bleeding
  • inhibit platelet aggregation
  • Warfarin effect
  • Lowered blood pressure (HYPOTENSION)
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12
Q

*Increase Risk of Bleeding
Used as a mood and energy level enhancer and to protect against stress and restore homeostasis?
-Lowers ___
-Inhibition of ___

A

Ginseng (panax quinquefolius/panax ginseng)

  • blood glucose
  • platelet aggregation
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13
Q

Side effects: transient nervousness, excitation, tachycardia, inability to concentrate, insomnia, headache, hypertension, epistaxis, allergies, water/electrolyte disturbances

A

Ginseng

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14
Q
  • Ginseng Concerns
  • At risk for ?
  • Potential to increase the ___
  • Caution in patients with ___ or on ___
  • May decrease effectiveness of ___
  • Avoid ??
A
  • Hypoglycemia
  • risk of bleeding
  • coagulopathies or on anticoagulants
  • Warfarin
  • ASA, NSAIDs
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15
Q
  • Increase Risk of Bleeding
  • Used for benign prostatic hypertrophy (BPH)
  • May have anti-inflammatory effects by inhibition of ___ and ___.
  • May increase bleeding
A
Saw Palmetto (Serenoa repens) 
-cyclooxygenase (COX) and platelet dysfunction
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16
Q

Used as weight loss aide, increased energy and asthma treatment?

  • Direct and indirect ??
  • Active ingredient is ?
A

Ephedra (Ma Huang)

  • sympathomimetic effects; CNS stimulant
  • Ephedrine
17
Q

Side effects: Hypertension, tachycardia, arrhythmias, vasoconstriction, vasospasm

A

Ephedra

18
Q
  • Ephedra Concerns:
  • Dangers include myocardial infarction, myocarditis, stroke, agitation, shaking, anxiety, insomnia, psychosis, seizures, nervousness, and panic attacks
  • Can develop ___ from depletion of ___
  • Life-threatening interaction with ?
A

tachyphylaxis
endogenous catecholamine stores - hemodynamic instability
MAOIs

19
Q

●March 2003, Baltimore Orioles pitcher Steve Bechler died. His death - and at least 154 others - have been linked to ephedra.
●The FDA announced in December 2003 it would ban the stimulant.
●Feb 6th 2004-Official ban on ephedra sales in any dietary supplement in US.
●Ruling overturned in Utah (only) in 2005.
●Also, on-line availability an issue

A

Ban on Ephedra

20
Q
  • Hypoglycemia
  • Short-term immune system stimulation
  • Used in prophylaxis and treatment of infections, esp URIs
A

Echinacea (echinacea purpurea)

21
Q
  • Echinacea Concerns
  • ___ = especially patients with asthma, atophy, allergic rhinitis
  • Decreased effectiveness of ___ (?)
  • Prolonged use may lead to overstimulation of ___ and ___
  • Contraindicated in pts with ___ = TB, leukosis, MS, HIV, other AI dzs
  • Worsen metabolic control in ___
  • Cause?
A
  • allergic reactions
  • immunosuppressive medications (corticosteroids)
  • immune system and immunosuppression
  • systemic disorders
  • diabetic patients - hypoglycemia
  • hepatotoxicity
22
Q

Used to treat insomnia, jet lag, shift work sleep aid

___ - Controls natural sleep-wake cycle

A

Melatonin

Hormone

23
Q
  • Readily crosses the blood-brain-barrier and increases sedative effects of hypnotics, benzodiazepines?
  • Has been studied as a preop anxiolysis drug
  • May interact w/ ????
A

Melatonin

anticoagulants, immunosuppressants, diabetic meds, BCP