Hepatology 2 Flashcards
Measures amount of time the blood takes to form a clot. CLIA waved test. Blue top tube
Prothrombin time (PT)
Critical element in production of prothrombin time
Vitamin K
Rate at which RBCs settle out of anticoagulant blood specimen after 30 minutes (mm/hr)
ESR- erythrocyte sedimentation rate
Abnormal condition of increased # of RBC
Polycythemia
Sickle shaped, caused by inherited Hgb-S molecule
Sickle cell
All blood elements show decrease, inability to produce cells in bone marrow
Aplastic
Deficient in vitamin B12/intrinsic factor is lacking cells appear enlarged and fragile
Pernicious
Increase in reticulocytes in peripheral blood due to RBC destruction caused by inherited thalassemia
Thalassemia and hemolytic
Most common type of anemia, inability to build healthy hgb caused by blood loss/inadequate iron in diet
Iron deficiency
Abnormal increase in # of WBC
Leukocytosis
Low WBC count, abnormal ( sign of aplastic anemia, HIV, chemo)
Leukocytopenia
Atypical reactive lymphocytes
Mononucleosis
Abnormal decrease in # of WBC
Leukopenia
Various cancers of WBCs
Leukemia
ALL
Acute lymphocytic leukemia (sudden onset)
CML
Chronic myeloid leukemia (ongoing)
Affects lymphoblasts
Microhemarocrit lab procedure
2 capillary tubes
Counter balance and centrifuge for 5 minutes
Capillary results should be within 2% of eachother
Hematocrit tubes
Contain heparin
Spun hematocrit tubes
Yellow-plasma
Buffy coat (WBC & platelets)
Orange- RBC
Bottom-clay/seal
CBCs
Consist of 7 lab tests
Cou noted and reported in millions per cubic millimeters million/mm3
RBC total count
% of packed RBC
Hematocrit- HCT
amount of hemoglobin released released after RBCs have been hydrolyzed. RBC is measured
Hemoglobin- Hgb
RBC indices- what are they used to diagnose and ratio elements
Causes of anemia and polycythemia
