Hepatobiliary Flashcards

1
Q

How much does the liver weigh?

A

1.3 kg (3 lbs)

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2
Q

Clinical significance of the liver

A
  1. Maintains immune function
  2. Maintains proper blood glucose levels
  3. Eliminates wastes
  4. Metabolism of drugs
  5. Bile secretion and production of bile salts
  6. CHO, lipid, protein metabolism
  7. Storage of minerals and vitamins
  8. Synthesis of plasma proteins and clotting factors
  9. Indirectly regulates BP & fluid levels
    A. through synthesis of plasma proteins
  10. If/When a portion of liver is damaged, it has ability to regenerate functional hepatocytes
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3
Q

How does the liver function via Detoxification?

A
  1. Phagocytize old or damaged RBCs
  2. Hormones and drugs are metabolized by hepatocytes
  3. Cytochrome p450
    A. Highest conc in liver cells
    B. Need proteins to create these enzymes
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4
Q

How does the liver function as regulation of CHO, lipid, & protein metabolism?

A

Liver receives absorbed nutrients via portal vein and processes them according to need

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5
Q

What are the fat soluble vitamins?

A

A,D,E,K,B12, folate

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6
Q

When tag is removed from VLDL what does it become?

A

LDL

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7
Q

LDL level should be?

A

less than 100

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8
Q

Optimal HDL level

A

40 for men

50 for women

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9
Q

Total cholesterol level?

A

less than 200

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10
Q

BMI: greater than 25 means?

A

Overweight

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