Hepatobiliary Flashcards
1
Q
How much does the liver weigh?
A
1.3 kg (3 lbs)
2
Q
Clinical significance of the liver
A
- Maintains immune function
- Maintains proper blood glucose levels
- Eliminates wastes
- Metabolism of drugs
- Bile secretion and production of bile salts
- CHO, lipid, protein metabolism
- Storage of minerals and vitamins
- Synthesis of plasma proteins and clotting factors
- Indirectly regulates BP & fluid levels
A. through synthesis of plasma proteins - If/When a portion of liver is damaged, it has ability to regenerate functional hepatocytes
3
Q
How does the liver function via Detoxification?
A
- Phagocytize old or damaged RBCs
- Hormones and drugs are metabolized by hepatocytes
- Cytochrome p450
A. Highest conc in liver cells
B. Need proteins to create these enzymes
4
Q
How does the liver function as regulation of CHO, lipid, & protein metabolism?
A
Liver receives absorbed nutrients via portal vein and processes them according to need
5
Q
What are the fat soluble vitamins?
A
A,D,E,K,B12, folate
6
Q
When tag is removed from VLDL what does it become?
A
LDL
7
Q
LDL level should be?
A
less than 100
8
Q
Optimal HDL level
A
40 for men
50 for women
9
Q
Total cholesterol level?
A
less than 200
10
Q
BMI: greater than 25 means?
A
Overweight