Hepatitis/Liver Disease Flashcards

1
Q

Sovaldi

A

Sofosbuvir

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2
Q

Harvoni

A

Sofosbuvir + ledipasvir

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3
Q

Epclusa

A

Sofosbuvir + Velpatasvir

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4
Q

Vosevi

A

Sofosbuvir + Velpatasvir + Voxilaprevir

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5
Q

Mavyret

A

Glecaprevir + Pibrentasvir

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6
Q

Viekira Pak

A

Paritaprevir/ritonavir/Ombitasvir + Dasabuvir

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7
Q

Suffix for NS3/4A PIs

A

-previr

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8
Q

Suffix for NS5A replication complex inhibitors

A

-asvir

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9
Q

Suffix for NS5B polymerase inhibitors

A

-buvir

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10
Q

Zepatier

A

Elbasvir/grazoprevir

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11
Q

HCV treatment algorithm

A

2-3 DAAs +/- ribavirin x 12 weeks

Mavyret x 8 weeks

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12
Q

Pan-genotypic DAAs

A

Epclusa, Mavyret

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13
Q

DAAs that have DDI with acid suppressant therapy

A

Harvoni, Epclusa, Vosevi

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14
Q

DAAs that treat HCV/HIV co-infection

A

Harvoni, Epclusa, Mavyret

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15
Q

DAAs salvage therapy

A

Vosevi, Mavyret

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16
Q

Ribavirin SE

A

Teratogenic, hemolytic anemia

17
Q

Drugs used to treat HepB

A

(NRTIs) TDF, TAF, lamivudine, telbivudine, entecavir, adefovir

18
Q

Hepatotoxic drugs (d/c if LFTs > 3x ULN)

A

APAP, isoniazid, nevirapine, NRTIs, tipranavir, valproic acid

19
Q

Drugs for relapse prevention for alcoholic liver disease

A

Naltrexone (ReVia, Vivitrol)
Acomprasate (Campral)
Disulfiram (Antabuse)