Hepatitis - incubation periods, routes of transmission, patho Flashcards
What is the incubation period for Hepatitis A?
Incubation period of 30 days
What is the routes of transmission for Hepatitis A?
Fecal-Oral(most common), parenteral, sexual
What is the patho behind Hepatitis A?
Hepatocyte injury caused caused by cellular immune responses (T cells, NK Cells, and cytokines)
What is the incubation period Hepatitis B?
60-180 days
What is the route of transmission of hepatitis b?
Parental, sexual, across placenta
Patho behind hepatitis b?
Viral replication, coinfection with viral mutation, inflammation, and cellular necrosis
What is the incubation period of hepatitis c?
35-60 days
What is the routes of transmission of hepatitis c?
Parental, sexual, across placenta
What is the patho behind hepatitis c?
Hepatocyte injury caused bu immune response, inflammation and fibrosis leading to cirrhosis
What is the incubation period of hepatitis d?
30-180 days
What is the route of transmission for hepatitis d?
HBV coinfection. Paranteral(?), fecal oral, sexual
Patho behind hepatitis d?
Coinfection with HBV, severe cell injury, inflammation progressing to cirrhosis
Incubation period of Hepatitis E?
15-60 days
Route of transmission of hepatitis E?
Fecal-oral
Patho behind hepatitis E?
Viral replication, liver is cytotoxic, immune response causes inflammation and cholestasis
