Hepatitis D

Question 1

Hep D can only replicate in the presence of which other sub-type of hepatitis?

Answer 1

HBV - 5% of HBV carriers have HDV co-infection.

Question 2

What is the aetiology of Hep D?

Answer 2

· Incomplete RNA virus.

· Activated by the presence of HBV so it is unable to replicate on its own.

Question 3

What is the treatment for Hep D?

Answer 3

· Mainly supportive treatment, Hep D can also be treated with pegylated interferon alpha (for a minimum 48 weeks) and liver transplantation which can be curative.

· Prevention and control of HDV infection requires prevention of HBV transmission through hepatitis B immunization
&raquo_space;> but hepatitis B immunization does not provide protection against HDV for those already HBV infected.