Hepatitis C Flashcards

1
Q

What is incubation period of hepatitis C?

A

Incubates over six to seven weeks.

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2
Q

T/F: with hepatitis C, typically asymptomatic, indolent, prolonged course until advanced liver disease develops.

A

TRUE

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3
Q

Is HIV or Hepatitis C the most common blood borne infection in the US?

A

Hepatitis C

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4
Q

What initial test do we order if we suspect hepatitis C?

A

Screens for HCV antibodies.

Detects antibodies 28–90 days after exposure.

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5
Q

What test do we order to confirm diagnosis of hepatitis C?

A

HCV RNA+ one to two weeks after infection

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6
Q

Which type of hepatitis C is most common in the US?

A

Type 1 HCV

***Type 1 more resistant to treatment

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7
Q

What medications are used for treatment of chronic hepatitis C?

A
Ribavirin 
pegylated interferon
telaprevir 
boceprevir 
simeprevir 
sofosbuvir
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8
Q

What is the duration of treatment for chronic hepatitis C?

A
Duration 6–12 months
Depending on: 
Genotype
Viral load
Liver biopsy results
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9
Q

Which type (s) of hepatitis are associated with hepatocellular carcinoma?

A

Associated with both HBV and HCV.

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10
Q

How do we monitor for hepatocellular carcinoma?

A

Test alpha fetoprotein, liver ultrasound every six months.

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11
Q

Babies who are exposed will retain mother’s antibodies for _____________ months?

A

12-18 months

Pronounced clear if they test negative after age 18 months

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12
Q
Infection with nontuberculosis mycobacteria
Previous BCG vaccination
Incorrect method of TST administration
Incorrect interpretation of reaction
Incorrect bottle of antigen used
A

The causes of false-positive reactions

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13
Q

Cutaneous anergy (anergy is the inability to react to skin tests because of a weakened immune system)
Recent TB infection (within 8-10 weeks of exposure)
Very old TB infection (many years)
Very young age (less than 6 months old)
Recent live-virus vaccination (e.g., measles and smallpox)
Overwhelming TB disease
Some viral illnesses (e.g., measles and chicken pox)
Incorrect method of TST administration
Incorrect interpretation of reaction

A

The causes for false-negative reactions

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