Hepatitis Flashcards

1
Q

How are Hepatitis A & E transmitted?

A

Fecal-Oral route (the vowels are in the bowls)

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2
Q

How are hepatitis B, C, and D transmitted? What are their most common modes of transmission?

A

Body fluids
B-Sex
C-IV drug use
D-from hep B (same mode)

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3
Q

Which hepatitis strand(s) have a vaccine? When are they given?

A

A & B

A: 2 doses, 6 months apart, part of the pediatric immunizations
B:3-4 doses over 6-18 months, peds immunization schedule and high risk groups (healthcare workers)

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4
Q

Which strands of hepatitis are acute? Which can turn chronic?

A

Acute: A&E
Can turn: B, *C, D

*rate of chronic illness is high

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5
Q

Which strands require supportive treatment? Which require medication?

A

A & E require only supportive treatment

B, C, and D require antiviral medications (Pegasus/interferon)

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6
Q

What does a positive IgM mean?

A

An active hepatitis infection

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7
Q

What does a positive IgG mean?

A

The patient has been vaccinated for Hep or has had a Hep infection and is immune to it

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8
Q

What is the post exposure protocol for Hep?

A

A: Immune globin (IG)within 2 weeks of exposure
B: IG within 24 hours of exposure (12 after birth if transmitted via child birth)
C: NONE
D: NONE
E: NONE

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9
Q

What other viruses can cause hepatitis/hepatitis like s/s? (Attack the liver)

A

Epstein Barr
Herpes simplex
Varicella Zoster
Cytomegalovirus

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10
Q

What are some hallmark s/s of hepatitis?

A

Jaundice/Icterus (dark urine, clay stools)

N/V/D, constipation, loss of appetite, ABD pain (Upper R Quadrant)

Fever, malaise, lethargy

Arthralgia, myalgia

Pruritus (itching)

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11
Q

When is a patient with hepatitis contagious?

A

Can be for up to 2 weeks BFORE s/s and 1-3 weeks AFTER s/s

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12
Q

What does a positive HBsAg mean?

A

Patient has a current Hep B infection

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13
Q

What does a positive Anti-HBs mean?

A

Patient has recovered from Hep B and is immune or is immune due to immunization

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14
Q

What is a normal ALT level? Will it elevate or decrease when infection is present?

A

7-56, elevate

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15
Q

What is a normal AST? Will it elevate or decrease when infection is present?

A

10-40, elevate

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16
Q

What is a normal bilirubin level?

A

<1

17
Q

What is a normal ammonia level? Will it increase or decrease with infection?

A

15-45, increase

18
Q

What is the most common indication of ammonia toxicity?

A

Mental status changes, confusion

19
Q

What does lactulose do?

A

Decreases ammonia by flushing from the GI via diarrhea

20
Q

What are the phases of hepatitis?

A

Preicteric/prodromal: body s/s (joint pain, fatigue, and pain, billi/AST/ALT elevated if tested)

Icteric: decreased body s/s, jaundice, enlarged liver and pain

Posticteric/convalescent: jaundice resolves, liver enzymes/billi decrease