Hepatitis Flashcards
What is the normal hepatitis picture?
High AST and ALT, normal ALP.
What is special about hepatitis D?
IT can only exist if the patient is infected by hepatitis B - because it binds to the HepB surface antigens.
What are the blood tests for Hep B?
- Surface antigen - positive in vaccine or infection
- core antigen - never positive in blood
- E antigen - positive in acute infection
- surface antibody - positive in current infection or after vaccination
- core antibody - IgM - acute infection, IgG - chronic infection
- E antibody - once Acute phase has passed and the body has dealt with it efficiently.
How is autoimmune hepatitis treated?
High dose prednisolone, then other life long immune suppressants - like azothiaprine.
How many people develop chronic Hepatitis C?
3/4 people with Hep C develop chronic infection, 90% who get treatment are cured.
How is Hep A spread?
Faecal-oral route.
What is the incubation period for Hep A?
28 days
How is Hep B spread?
Sexually
What is the incubation period for Hep B?
90 days
How is Hep c spread?
sexually
What is the incubation of Hep C?
60 days
What is the spread of hep D?
Parenteral
What is the incubation period of Hep D?
20-50
What is the transmission of Hep E?
Faecal oral
What is the incubation period of Hep E?
40 days
