Hepatic FUNCTION TEST Flashcards
Albumin
3.5 to 5.0
AST
0 to 35 U/L
ALK Phos
30 to 120 U/L
ALT
4 to 36 U/L
BILIRUBIN
0.3 1.0 mg/dL
Direct Bili
0.1 to 0.3 mg/dL
Ammonia
10 to 80 mcg/dL
A protien found and syntized within the liver.
Albumin
Comprises of 60% of total protien in blood
Albumin
Regulates osmotic pressure
Albumin
Transport blood, hormones,enzymes, and drugs.
Hepatic function and nutritional state
Albumin
High Albumin
Dehydration
Malnutrition.preganncy
Liver disease
Protein losing enteropathies
Protien losing nephropathies
Third space losses
Over hydration
Increased capillary permeability
Inflammatory disease
Familial idiopathic dysproteinemia
Low in Albumin
Alkaline phosphate ALP
30 to 120 u/L
Detect and monitor deiseases of liver and bone
Alkaline phosphatase ALP
High in Alkaline Phosphatase
Primary cirrhosi
Intrahepatic extrahepatic biliary obstruction
Primary or metastatic live tumor
Metastatic tumor to the bone
Healing fracture
Osteomalacia
Paget disease
Rheumatoid aryhritis
Rickets.intestinal ischemia or infarcion
Myocardial infarctiosarcoidosis
Hypophosphatetemia
Hypophosphatasia
Malnutrition
Milk alkali sybdrome
Pernicious anemia
Scurvy vit c deficiency
Low in Alkaline phosphatase
Predominantly found in the liver
Alanine Aminitransferase ALT
Use to identify and monitor hepatocwllular disease of the liver
ALT or Alanine Aminostransfwrase ALT
If injury or disease affecting the liver parenchyma what will release in the bloodstream
ALT release
Very high ALT
Hepatitis liver
Hepatic necrosis
Hepatic ischemia
Moderately high ALT
Cirrhosis
Chokestasis
Hepatic tumor
Hepatoxic drugs
Obstructive jaundice
Severe burns
Trauma to striated muscle
Mildy high
Myositis
Pancreatitis
Myocardial infarcion
Infectious mononucleaosis
Found in very high concentrations within highly metabolic tissues
Aspartate Aminotransferase AST
Disease injury of on the tissue dying cells release into the blood stream
AST
Use for evaluation of pt with suspected hepatocellular disease
AST
High Ast
Liver disease
Skeletal muscle trauma
Low AST
Acute renal disease
Beriberi
Diabetic ketoacidosis
Chronic renal dialysis
Component of bile
Bilirubin
End product of rbc metabolism
Bilirubin
Jaundice
Bilirubin >2.5mg/dL
Unconjugated bilirubin
Level of indirect bilirubin in blood
0.02 to 0.08 mg /dL
Conjugated bilirubin
Level of direct bilirubin in blood
0.1 to 0.3
High conjugated bilirubin
Gallstone
Extra hepatic duct obstructions
Extensive liver mets
Cholestasis from drugs
Dubin johnson syndrom
Rotoe syndrome