Hepatic Disorder Drugs

Question 1

Octreotide [Sandostatin]

Answer 1

Synthetic Somatostatin Analogue
Anti-diarrheal

Esophageal Varices

Question 2

Interferon-a & PEG interferon a

Answer 2

Interferon

HBV; HCV

Question 3

Ofloxacin [Floxin]

Answer 3

Quinolone Abx

Traveler’s Diarrhea

Question 4

Ribavarin [Virazole]

Answer 4

Guanosine analogue antiviral
Eradication of HCV
not in PG warn male partners
PG HCW shouldnt handle drug b/c teratogenic

Question 5

Lamivudine [Epivir]

Answer 5

Cytosine Analogue Anti-viral (NRTI)
SUPPRESSES HBV
HIV

Question 6

Sofosbuvir [Sovaldi]

Answer 6

Direct acting anti-viral
Polymerase Inhibitor
Used in combo with Ribavarin for HCV Genotype 2 tx
(typical HCV reg= PEG inter + Rib + Sofos

Question 7

Ledipasvir/Sofosbuvir [Harvoni]

Answer 7

Direct acting anti-viral
Polymerase inhibitor
Harvoni has less SE/ADRs but super $$$$

Question 8

Rifaximin [Hifaxan]

Answer 8

Misc Abx
alternates bacterial flora to have safe effect like lactulose
2nd choice for Hepatic encephalopathy

Question 9

Hep A Vaccine [Harvix]

Answer 9

Inactivated Vaccine

Question 10

Hep B Vaccine [Engerix-B]

Answer 10

Recombinant Vaccine