Heparinization

Question 1

Two sources of Heparin

Answer 1

beef lung and pork intestinal mucosa; The porcine (pork) derivative is more potent than the beef lung heparin.

Question 2

Drugs that enhances heparin

Answer 2

aspirin
nonsteroidal anti-inflammatory agents (NSAIDS)
dextran

Question 3

Drugs that decreases heparin effect

Answer 3

nicotine
cardiac glycosides
quinine
tetracycline

Question 4

Commonly used heparin concentration for dialysis?

Answer 4

1000u/ml

Question 5

What is Regional Heparinization?

Answer 5

the continual infusion of heparin via the arterial line with
a concurrent infusion of an antidote into the venous line before the blood is infused back into the patient.

Question 6

Major disadvantages of regional heparinization?

Answer 6

numerous laboratory tests are required to assess the clotting time and calcium levels

Question 7

What is Tight Heparinization?

Answer 7

also known to as low-dose heparinization, refers to the
technique of heparin administration in which the dosage is determined by frequent clotting times in order to maintain a clotting time of 90-120 seconds by ACT.

Question 8

Heparin free HD?

Answer 8

> done without the use of an anticoagulant is the therapy of choice for patients with an increased risk of bleeding, pericarditis, coagulopathy, or thrombocytopenia.
rinsed with 100-200 mL of saline as frequently as every 15 minutes up to once every hour, through the arterial line, and is inspected for clotting