hep A

Question 1

spread - hep A

Answer 1

fecal-oral route

food etc in travellers

Question 2

CF - hep A

Answer 2

1. jaundice

2. hepatosplenomegaly

Question 3

comp - Hep A

Answer 3

1. does not increase risk of hepatocellular carcinoma

2. no chronic disease

Question 4

spread hep B

Answer 4

infected blood or bodily fluids

Question 5

comp hep - b

Answer 5

1. chronic hep - glass-ground hepatocytes on light microscopy
2. hepatocellular carcinoma

Question 6

mx - hep B

Answer 6

pegylated interferon - alpha

Question 7

first marker after hep B infection?

Answer 7

HBsAg - first marker to appear and causes production of anti-HBs

Question 8

1. HBsAG for < 6 months

2. HBsAG for > 6 months

Answer 8

1. acute hepatitis B

2. chronic hepatitis B

Question 9

what does anti-HBs mean

Answer 9

1. positive - immunity via infection or vaccination

2. negative - chronic disease

Question 10

what does HbeAg indicate?

Answer 10

breakdown of core antigen - marker of infectivity

Question 11

Hep C - spread

Answer 11

IV drug use / blood borne

Question 12

Diagnosis of hep C

Answer 12

HCV RNA

Question 13

what does anti-HCV indicate?

Answer 13

Hep C antibodies which will remain even after indivisual has cleared the investction

Question 14

chronic hep C -

Answer 14

1. cirrhosis

2. hepatocellular carnicoma

Question 15

Mx - hep C

Answer 15

protease inhibitors - end in ‘vir’