Hemotology Flashcards
Hgb values
12-16 females
13.5-18 males
RBC values
4-5 females
4.5-6 males
Hemoglobin and anemia values
10-14 mild
6-10 moderate
<6 severe
3 signs symptoms of severe anemia
Fatigue
Palpitations
Dyspnea
Hct values
3 times the Hgb value
If Hct is elevated then the patient is experiencing…
Fluid volume deficiet
If Hct is decreased then the patient is experiencing…
Fluid volume overload/ excess
WBC values
4000-11000
Neutrophils should be….
50-78% of wBCs
Neutropenia actions
Temp greater 100.4/38C report immediately and start IV antibiotic
Shift to left is high neutrophil= severe infection
Platelet values
100,000-250,000
Thrombocytopenia platelet count
Less than 100,000
Thrombocytopenia critical values
Critical less than 50,000
Hemorrhage if less than 20,000
Need platelet transfusion if less than 10,000
INR values for Coumadin therapy
INR values for No therapy
Coumadin = 2-3
No therapy= 1-2
Antidote for Coumadin therapy
Intramuscular injection Vitamin K
Coumadin is part of the ——–pathway for coagulation
Extrinsic
aPTT values for heparin therapy
aPTT vales for no therapy
aPTT Heparin critical value
Heparin therapy 75-112
1.5-2.5 times normal
No therapy 25-35 seconds
Critical greater than 130–heparin protocol
Antidote to heparin therapy
Protamine sulfate
Heparin is part of the——–pathway
Intrinsic
Patient teaching for iron liquid supplement
Where is IM iron injections given, by which method?
Acidic stomach, empty stomach, vitamin C increases absorption, causes black tarry stools and constipation. Stains teeth, drink with straw.
Deep gluteus with z-track
What is hydroxyurea (Hydrea)?
Medications used to increase fetal hemoglobin in sickle cell and leukemia patients
What is cyanocobalamin?
Medication for vitamin b12 deficient anemia. Available PO and IM.
What is the side effects of cyanocobalamin medication?
Decreased K+, secondary to improved RBC production and may need supplemental K+
What is the action of folic acid?
Increases production of RBCs; also prevents neural tube defects.
What are Epogen and Procrit used for?
Increase production of RBC in bone marrow for chemo and renal failure patients.
Watch for HTN secondary to increased Hct.
What are the uses of Neupogen?
Stimulate bone marrow production of neutrophils /WBC to decrease Risk of infection.
Watch for nine pain, notify mad and give Tylenol
What lab values are reduced in anemia?
Decreased RBC, Hgb and Hct
Patients with pernicious anemia lack what?
Intrinsic factor needed in the stomach to absorb vitamin b12
Define vitamin b12 anemia.
Decreased RBCs secondary to decreased b12. But have large RBCs.
Decreased cobalamin serum levels
Vitamin b12 is water soluble.
Define folic acid anemia
Decreased RBCs secondary to decreased serum folate.
What is the shillings test? How performed? How to interpret results?
Shillings is radioactive urine test for determining absorption of vitamin b12. 24 hour urine collection. If b12 found in urine then not absorbing it-lack intrinsic factors.
What are sources of dietary vitamin b 12?
Eggs, dairy, animal proteins
What are dietary sources of folic acid?
Fruits green leafy vegetables.
What are symptoms of vitamin b12 anemia
Fatigue, dyspnea, palpations
Parathesias, swollen red tongue, confusion.
What are some common causes of vitamin b12 anemia?
Decreased diet intake Alcoholism Digestive disorders (chroma/celiac) Wt loss surgery Antacids (PPIs ⬇️acid needed to absorb iron).
HOP is used for the treatment of ——
Sickle cell anemia.
Hydration
Oxygenation
Pain
What are triggers for sickle cell anemia?
Anything that decreased oxygen -hypoxemia
Infection
Dehydration
Hypoxemia
What organs are damaged in sickle cell anemia?
Spleen-RBCs get caught up
Liver-jaundice from hemolysis of Hgb