Hemotologic Emergencies Flashcards
What history is sometimes seen with anemia?
Anorexia Pica Lethargy Collapse Syncope See if they are on any medications Exposures to parasites, toxins, or heat Any recent blood loss (hematuria, melena, hematochezia, epistaxis, hemoptysis)
What physical exam findings are seen with anemia?
Pale mucous membranes Ecchymoses Grade I-II/ VI heart murmur Bounding pulses Tachycardia Rectal exams show melena
What PCV indicates severe anemia in the dog?
< 18%
What PCV indicates moderate anemia In the dog?
18-29%
What PCV indicates mild anemia in the dog?
30-36%
What red blood cell parameters indicate regenerative anemia?
Macrocytic (increased MCV)
Hypochromic (decreased MCHC)
Retticulocyte count > 60,000
Reticulocyte index > 2.5
What values are seen with hemolytic anemia?
Strong to moderate regenerative response
Leukocytosis
Neutrophilia with left shift
Monocytosis
What is a normal manual platelet count? What is a clinically significant thrombocytopenia on manual count?
8-12/ hpf
3-4/ hpf is clinically significant
What is the difference between blood loss and hemolysis with hypoproteinemia?
Blood loss will usually have hypoproteinemia
Hemolysis will be normal
What is measured with ACT?
Intrinsic and common pathway
What is measured with PT?
Extrinsic and common pathway
What is measured with PTT?
Intrinsic and common pathway
What rate should be used for red blood cell administration?
5-10 mL/kg/hr
When should you be checking PCV after giving a blood transfusion?
1hr, 24 hr, 72hr
What immunosuppressive drugs can be used in patients with IMHA that continue to display anema?
Pred Dex Azathiaprine Cyclophoshamide Mycophenolate Splenectomy in cases refractory or with clinical signs Leflunomide Cyclosporine If patient is stable, wean off meds by 25% every 2 weeks through 6 weeks