Hemotologic Emergencies Flashcards

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1
Q

What history is sometimes seen with anemia?

A
Anorexia
Pica
Lethargy
Collapse
Syncope
See if they are on any medications
Exposures to parasites, toxins, or heat
Any recent blood loss (hematuria, melena, hematochezia, epistaxis, hemoptysis)
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2
Q

What physical exam findings are seen with anemia?

A
Pale mucous membranes
Ecchymoses
Grade I-II/ VI heart murmur 
Bounding pulses
Tachycardia
Rectal exams show melena
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3
Q

What PCV indicates severe anemia in the dog?

A

< 18%

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4
Q

What PCV indicates moderate anemia In the dog?

A

18-29%

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5
Q

What PCV indicates mild anemia in the dog?

A

30-36%

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6
Q

What red blood cell parameters indicate regenerative anemia?

A

Macrocytic (increased MCV)
Hypochromic (decreased MCHC)
Retticulocyte count > 60,000
Reticulocyte index > 2.5

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7
Q

What values are seen with hemolytic anemia?

A

Strong to moderate regenerative response
Leukocytosis
Neutrophilia with left shift
Monocytosis

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8
Q

What is a normal manual platelet count? What is a clinically significant thrombocytopenia on manual count?

A

8-12/ hpf

3-4/ hpf is clinically significant

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9
Q

What is the difference between blood loss and hemolysis with hypoproteinemia?

A

Blood loss will usually have hypoproteinemia

Hemolysis will be normal

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10
Q

What is measured with ACT?

A

Intrinsic and common pathway

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11
Q

What is measured with PT?

A

Extrinsic and common pathway

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12
Q

What is measured with PTT?

A

Intrinsic and common pathway

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13
Q

What rate should be used for red blood cell administration?

A

5-10 mL/kg/hr

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14
Q

When should you be checking PCV after giving a blood transfusion?

A

1hr, 24 hr, 72hr

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15
Q

What immunosuppressive drugs can be used in patients with IMHA that continue to display anema?

A
Pred
Dex
Azathiaprine
Cyclophoshamide
Mycophenolate 
Splenectomy in cases refractory or with clinical signs
Leflunomide
Cyclosporine
If patient is stable, wean off meds by 25% every 2 weeks through 6 weeks
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16
Q

What PCV indicated severe anemia in the cat?

A

< 14%

17
Q

What PCV indicated moderate anemia in the cat?

A

15-19%

18
Q

What PCV indicated mild anemia in the cat?

A

20-24%

19
Q

What medication is useful for cat with non-responsive IMHA?

A

Chlorambucil

20
Q

What is considered a mild thrombocytopenia in the dog?

A

<100000

21
Q

What is considered a moderate thrombocytopenia in the dog?

A

<60,000

22
Q

What is considered a severe thrombocytopenia in the dog?

A

< 30,000

Associated with increased risk of hemorrhage

23
Q

What is the equivalent of 1 platelet per high powered field?

A

15,000

24
Q

What is normal buccal mucosal time in dogs?

A

2-3 minutes

Prolonged with thrombocytopenia, thrombocytopathia, von Willebrand’s

25
Q

What breeds are associated with factor I deficiency?

A

Saint Bernards
Vizslas
Collies
Borzois

26
Q

What breeds are associated with factor II deficiency?

A

Boxers
Cocker Spaniels
Devon Rex cats

27
Q

What breeds are associated with factor VII deficiency?

A
Beagles
Alaskan Malamutes
miniatures Schnauzers
Boxers 
English Bulldogs
28
Q

What breeds are associated with factor VIII deficiency?

A

mixed breeds

Devon Short Hair

29
Q

What places should you check for on physical exam for coagulopathies?

A
Subcutaneous tissues
Muscles
Hematoma
Petechia
Ecchymoses on oral, scleral, penile, vulvar, conjunctival mm)
Joints
Icterus
30
Q

What signs are seen with coagulopathies?

A

Hematomas are common
Bleeding is localized, common in muscles and joints
Delayed at first then start again
Petechiae are rare

31
Q

What signs are seen with platelet or vascular disorders?

A

Petechiae are common
Bleeding in multiple locations, mucous membranes common
Prolonged bleeding time from cuts
Hematomas are rare

32
Q

What is the recommended treatment for von Willebrands? What is a suitable alternative?

A

Cryoprecipitate is ideal

Fresh frozen plasma is an alternative

33
Q

How should yunnan baiyao be dosed?

A

5 days on, 5 days off

34
Q

What is the prognosis for DIC?

A

Guarded to poor

35
Q

What is the most common cause of hemoperitoneum?

A

Trauma (HBC, kicked, gunshots, dog fight, foreign body)

36
Q

When should whole red blood cells be given to patients?

A

When PCV < 25%

37
Q

When should plasma be administered to patients?

A

When TS < 4.0