Hemostasis Flashcards
What test monitors patients who are on Warfarin or Coumadin therapy?
PT/INR
What pathway does warfarin or Coumadin affect?
Extrinsic
What test monitors patients who are on heparin therapy?
PTT
What pathway does heparin affect?
Intrinsic
What anticoagulant is used for coagulation tests? What color vacutainer is it?
Sodium citrate / light blue tube
Coagulation tests are performed on?
Plasma
Why must blood collection for coagulation tests be performed carefully?
To ensure minimum trauma to veins and surrounding tissues that may release chemicals and result in activation of the coagulation pathway.
What are 2 inhibitors of platelet aggregation?
Plavix and aspirin
What does Coumadin/warfarin inhibit?
The production of vitamin K dependant factors
What does heparin inhibit?
Activate of some coagulation factors
What does a D-Dimer test detect?
The breakdown products of a blood clot.
Hemophilia A Is due to a deficiency of what?
Factor VIII
Hemophilia B is a deficiency of what?
Factor IX
What is the most common inherited platelet disorder?
Von willebrand’s disease (vWD)
What does Von Willebrand’s Disease affect?
Platelet adhesion