Hemostasis Flashcards
Why are platelets hard to count?
They easily disintegrate
Small, colorless, refractile bodies
Difficult to distinguish from debris
unevenly distributed in the blood
tend to attach to foreign surface
tend to clump with each other
What factors are present in fresh plasma?
Factor I, II, V, VII, VIII, IX, X, XI, XII, XIII
(All factors)
What factors are present in adsorbed plasma?
Factor I, V, VIII, X, XII, XIII
Factors absent in adsorbed plasma
Factor IX, X, VII, III
Factors present in aged plasma
Factor I, II, VII, IX, X, XI, XII, XIII
What factors are absent in aged plasma?
Factors V and VIII
Factors present in normal serum
Factor II (20%), VII, IX, X, XI, XII
Factors absent in the normal serum
Factor I, V, VIII, XIII
Why do normal serum and aged serum have an absence in Fibrinogen group?
They are consumed during the clotting process
What differenciates the normal serum from the aged serum?
Aged serum has no Factor II
What is the best indirect method of quantifying platelets?
Olef’s method
What is the most accurate method of counting platelets?
Direct method
What does the bleeding time test for?
Measures the time required for the bleeding to stop
What is the method of testing the bleeding time using the pricking of the earlobe or the finger?
Duke method
What is the normal value of duke method?
2-4 minutes