Hemolytic anemias and other types of hemolysis Flashcards
1
Q
what increases due to intravascular hemolysis? cna this also occur in extravascular?
A
plasma hemoglobin, serum bilirubin and lactate dehydrogenase, and urine urobilinogen.
presence of hemoglobinuria and hemosiderinuria;
IN excessive extravascular there can be hemoglobinemia and decreased haptoglobin levels
2
Q
what decreases due to intravascular hemolysis?
A
serum haptoglobin
3
Q
what happens to all the components of RBCs in extravascular hemolysis?
A
the protoporphyrin rings are metabolized into bilirubin and urobilinogen; the globin chains recycled into the amino pool; the iron carried by transferrin to marrow for new cells or storage as ferritin or hemosiderin
