Brainscape's Knowledge GenomeTM


Top Flashcards (Certified)
All Flashcards

Meg's > Hemolymphatics > Flashcards

Hemolymphatics Flashcards

1
Q

What cells do combined immunodeficiency disorders (CIDS) affect? TQ

A

Both Humoral (B cells)and Cell mediated immunity (T cells)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What breed does equine CID affect, eitology & sequele?

A

ArabiansInheritedFailure of function of B and T lymphocyte production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Who gets XSCID? What is the sequele?

A

Dogs- bassets & welsh corgisMales lack mature functional T lymphocites, low IgG & IgA w/ normal IgM

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What do degenerative Thymus disorders result in?

A

Variable degrees of aquired immunodefeciency

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the degenerative disorders of the Thymus?

A

AtrophyLoss of ArchitectureLymphocyto-lysisReduced lymphocyte populations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What neoplastic disease of the Thymus affects young animals?

A

Thymic Lymphoma (T-lymphocyte neoplasm)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is thymoma?

A

Thymic epithelial cell neoplasm w/ mix of non-neoplastic lymphocytes.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Are thymoma’s benign or malignant, what age animal do they occur in?

A

Usually BenignSeen in older animals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What other dz’s are associated with thymomas? (TQ)

A

Myasthenia gravis +/- megaesophagusImmune mediated polymyositis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What causes thymic hemorrahage and hematomas,? What species?Sequele?

A

Trauma, ruptured aortic aneurisms, Rodenticide poisoningDogsSudden hypovolemic shock

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What are the two types of physical injury could happen to the spleen? TQ

A

Rupture-HBC, neoplasm rupture (hemangio(sarco)ma/lymphosarcoma), SplenomegalyTorsion- strangulation of pole pigs, GDV dogs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What are the three types of splenic degeneration and necrosis?

A

SiderofibrosisAmyloidosisHemosiderosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What is siderfibrosis, the lesions and who gets it?

A

Sidero-calcific plaques of capsule “gamna-Gandy bodiesFibrosis of capsule, hemosiderosis, granular encrustationsAged dogs

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What is amyloidosis & lesions?

A

“Sago Spleen”Prominent white pulp

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is hemosiderosis?

A

Pigmentation from hemosiderin (storage form of iron)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Eitology of hemosiderosis?

A

Breakdown of RBC’sDecrease erythropoiesis = less iron demandhemolytic anemiachronic heart failureIron dextran injection pigsHemorrhage (trauma)Hematomas,infarcts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What type of atrophy of the spleen is frequent in old dogs?

A

Nodular Hyperplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

When does extramedulary hematopoiesis happen in the spleen?

A

Young animals = normalcompensatory in anemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What can lead to uniform splenomegally with a bloody consistency “bloody spleen”?

A

Congestion- torsion, barbituate, euthanasia, sedationAcute hyperemia- septicimia, inflammationAcute hemolytic anemia- babesiosis, EIA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What can lead to uniform splenomegaly with a firm consistency “meaty spleen”? TQ

A

Chronic hemolytic anemia (EIA)Extramedullary hematopoiesis (EMH)Chronic infectious DzLympohid hyperplasiaBacteremia & low septicemiaNeoplasia (primary)Splenic myeloid mataplasia, histocytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What can lead to nodular spenomegaly with bloody nodules?

A

Hematoma from lymphoid hyperplastic nodules or splenic vascular neoplasmsIncomplete contractionAcute infarcts (wedge shaped)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What can lead to nodular splenomegaly with firm nodules?

A

Nodular hyperplasia- lymphoidPrimary neoplasmsMetastatic neoplasmsAbscesses- acute infectious dzGranulomas- chronic infectious dz

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What are the main causes of small spleens?

A

Developmental anomaliesAging changesWasting &/or cachectic DzSplenic contraction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

What is damaged in wasting &/or Cachectic Dz of spleen? TQ

A

Atropy of T-lymphocyte areasLittle-no effect on B lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

What are the Neoplastic Dz of the spleen?

A

LymphomaHemangiomaHemangiosarcomaMetastatic Neoplasms

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

What are the 3 ways lymph nodes response to injury?

A

Hyperplastic changesAtrophic ChangesInflammation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

What are the 5 things that can cause small lymphnodes?

A

Developmental disorders (SCID)Lack of antigenic stimulationCachexia & malnutritionAgingViral

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

What is the sequele of Cachexia & malnutrition on lymphnodes? TQ

A

Smaller than normal LNAtrophy of T areas –> decrease in T lymphocytes with little to no effect on B-lymphocytes

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

What are the agents and sequele of Viral infections on lymphnodes? TQ

A

Lymphocytolysis (BVDV, CDV)Stimulate Lymphiod Tissue (Maedi-Visna, MCFV)Neoplasia (FLV, BLV, Marek’s)Atrophy (FIV)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

What are the 3 causes of enlarged lymphnodes?

A

Lymphoid HyperplasiaLymphadenitisNeoplasa

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

What are the 2 types of lymphoid hyperplasia? TQ

A

Follicular (B-lymphocytes)Diffuse (T-lymphocytes)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

What are the two types of Lymphadenitis?

A

AcuteChronic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

What are the two types of Chronic Lymphadenitis?

A

Chronic Suppurative (active)Chronic Granulomatous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

What are the 2 types of Chronic Granulomatous and their etiological agents?

A

Focal granulomatous - tuberculosis (pearls dz), Crptococcus, ActinobacillusDiffuse Granulomatous- Histoplasmosis, Leishmaniasis, Johne’s dz (non caseating) “M paratuberculoisis”

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

What is the most common primary neoplasm of LN?

A

Lymphocarcomamalignant cells cause loss of architecture in cortex & medulla

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

What are two substances observed in LN?

A

Chyle (post prandial)Gas emphysema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

What growth disturbance of the LN is an important cause of lymphadenopathy?

A

Hyperplasia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

What are the 4 types of hyperplasia of the LN?

A

Follicular & diffuse lyphoid hyperplasiaAcute lymphadenitisChronic lymphadenitisNeoplasia (primary & metastatic)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

What is the difference microscopically between LN Neoplasia of the LN & Lymphoma? TQ

A

Neoplasia - Lack of capsular invasion & preservastion of architectureLymphoma- Capsular invasion & loss of architecture

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

What are the two types of lymphoma in cattle? TQ

A

Enzootic Bovine Leukosis (BLV)Sporadic Bovine Leukosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

Enzootic Bovine Leukosis affects cattle of what age? TQ

A

Adults 4-8 years

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

What virus is responsible for Enzootic Bovine Leukosis? TQ

A

Bovine Leukemia Virus (BLV) a retrovirus

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

What locations in cattle will you find the lesions of Enzootic Bovine Leukosis? TQ

A

“HAULS”HeartAbomasumUterusLNSpinal Canal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

Sporadic Bovine Leukosis affects cattle of what age group? TQ

A

Young animals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

Is Sporadic Bovine Leukosis associated with BLV?

A

No

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

What is the age group & distribution of calf/juvenile type of Sporadic Bovine Leukosis?

A

Calves up to 6 months oldMulticentric

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

What is the age group of calves affected with Thymic type Sporadic Bovine Leukosis?

A

1-2 year olds

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

What is the age group and lesion of cutaneous sporadic bovine leukosis?

A

2-3 year old cattleskin nodules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

What is the presentation of horses with lymphoma?

A

VariableMulticentricAlimentaryCutaneousSplenicAbdominal

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

What is the most common presentation of lymphoma in dogs? TQ

A

Multicentric LN, Liver Spleen bone marrowUnusual presentation b/c Normal architecture is present but cortex/medulla is obliterated

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

What causes lymphoma in cats & how does it present?

A

FeLVMulticentricAlimentaryThymicMiscellanous

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

Bone Marrow Response to injury?

A

AbnormalProliferationConcentrationStructure or function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

What is aplastic anemia? TQ

A

A type of abnormal proliferation leading to the absence of a particular hemopoietic lineage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

What is the absence of all hemopoietic lineages?

A

Aplastic pancytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

What can cause aplastic anemia?

A

Chemicals Infections

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

What chemicals cause aplastic anemia?

A

Phenylbutazone (horse, dog)Bracken Fern (cattle, sheep)Estrogen (dogs)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

What type of infections casue aplastic anemia?

A

Non-regenerative AnemiaEhrlichiosis–> BM hypoplasiaFeLV–> affects precurser cellsEIA–>cyclic infectionCytauxzoon felis–>excellerated RBC destruction/removalOtherParvoFIV–> anemia from concurrent dz

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

Whate is neoplasia of bone marrow called and where does it occur?

A

LeukemiaFrom bone marrow hematopoietic cells

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

How is Leukemia classified?

A

Cell of origion Lymphocytic (outside BM)Myelogenous (non-lymphoid origon)Degree of differentiationAcute- poorlyChronic- well

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

What is Myelophthisis? TQ

A

Replacement of hematopoietic tissue in BM by fibrous tissue, malignant cells or granulomas

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

What causes serous atrophy of fat in BM?

A

Cachexia/Starvation = gelatinous transformaitonBM reticular cells produce a mucoid substance. But hemoatopoietic cells & fat still found in BM

62
Q

What is lethal gray collie disease?

A

Cyclic Hematopoiesis –> inherited disorder of pluripotent hematopoietic stem cells

63
Q

What is cytopenia?

A

Deficiency of blood cells

64
Q

What is pancytopenia?

A

decrease in all hemopoietic cells

65
Q

When do hematopoietic cells deplete in Aplastic cytopenia (aplastic anemia)?

A

Neuts–>1wkPlatlets–>2wksRBC’s–>months

66
Q

What is persistent lymphocytosis?What species do you see it in?What causes it?TQ

A

Non-neoplastic hyperplasia of B-lymphocytes. Increases risk of developing B-lymphocyte lymphomaCattle (30% get lymphocytosis w/in 3 months)BLV infections

67
Q

Poikilocytosis?

A

Abnormally shaped RBC’s

68
Q

What are Toxic changes you would see in hematopoetic cells?

A

increased cytoplasmic basophiliaDohle Bodies: sm blue/grey cytoplasmic inclusions of aggregated endoplasmic reticulumCytoplasmic vaculations (severe)

69
Q

What is Pelger-Huet Anomaly (PHA)?

A

Lack of normal segmentation in nucleous of mature granulocytes (look immature)

70
Q

What is the mode of inheritance of PHA?

A

Autosomal dominant w/ incomplete penetranceHets–>not pathogenicHomo–>skeletal abnormalities, stillbirths, early mortality, granulocytes have round/oval nuclei

71
Q

What is pseudo-PHA?

A

Aquired reversible condition that mimics the real thing

72
Q

What does Pseudo PHA cause?

A

HypocoagulabilityHypercoagulabilityDisorders of hemostasis

73
Q

What type of bleeds happen with disorders of primary hemostasis?

A

Small bleeds

74
Q

What type of bleeds happen with disorders of secondary hemostasis?

A

Big bleeds

75
Q

What does intravascular hemolysis cause?

A

hemoglobinemiahemoglobinuriabillirubinuriaJaundice/Icterus

76
Q

What are the immune mediated disorders of RBC’s (3)

A

Primary IMHASecondary IMHANeonatal Isoerythrolysis (NI)

77
Q

What is the eitiology of Primary IMHA?

A

IdiopathicIgG>IgM

78
Q

What is secondary IMHA secondary to? (6)

A

InfectionDrugsChemicalsVaxNeoplasiaBee sting

79
Q

How does Neonatal Isoerythrolysis occur?

A

Colostrum derived maternal Ab react with newborn erythrocytes.

80
Q

What is babesia?

A

An intracellular Protoazoal parasite

81
Q

How does babesia cause hemolysis?

A

Extravascular hemolysis via immune mediated RBC destruction or oxidative damage. Intravascular hemolysis via protozoal proteases

82
Q

What are the lesions of babesiosis

A

SplenomegalyJaundice, hemoglobinuriaHemorrhageGallbladder distended with thick bile (choleostasis)

83
Q

What is cytauxzoon felis?

A

A protozal parisite of cats that causes severe, fatal dz.

84
Q

What does the scizogenouse phase of C. felis do?

A

schizont–>macrophage–>occlude veins–>Ischemia

85
Q

What does the Erythrocyte phase of C. felis do?

A

IV merozoites–>RBC’s__>Immune mediated EV hemolysis

86
Q

What type of anemia can C. Felis cuse?

A

Normocytic, Normochromic Nonregenerative anemia

87
Q

CS of C. felis?

A

Acute illness & feverpallor–>icterusDeath with in 2-3 days

88
Q

Do trypanosoma spp infect RBC’s?

A

No but cause immune mediated EV hemolysis

89
Q

What is the trifecta of CS with Babesia, Anaplasma & hemotropic mycoplasma?

A

Pallor–>icterusSplenomegalydistended gallbaldder

90
Q

What kind of parasite are Anaplasma species?

A

Rickettsial agentsIntracellular

91
Q

What Bacteria causes fatal hemolytic anemia? TQ

A

Clostridium

92
Q

How does Clostridium spp cause anemia? TQ

A

Bacterial toxins from the clostridium cause acute hemolysis

93
Q

What causes bacillary hemoglobinuria “red water” in cattle? TQ

A

Clostridium

94
Q

What causes yellow lamb dz?

A

CLostridium perfringens type A (enterotoxemic jaundice)

95
Q

Co-infection with liver flukes and one of these two types of bacteria can cause release if hemolytic toxins? TQ

A

CLostridium haemolyticum Clostriium novyi type D

96
Q

Hemotropic mycoplama is what kind of parasite and causes what?

A

Epicellular parasite–> invaginations of RBC surfaceImmune mediated EV hemolysis

97
Q

Leptospira spp. cause what type of hemolysis?

A

Extravascular hemolysis via immune mediated Intravascular hemolysis via enzymatic (phospholypase production)

98
Q

What agents cause Intravascular hemolysis?

A

BabesiaCLostridiumLeptoEIAHYPO-PWater IntoxAcute PFK deficency

99
Q

What are the CS of Acute EIA? TQ

A

ThrombocytopeniaAnemiaFever

100
Q

What are the CS of chronic EIA?

A

IcterusLymphadenopathy”meaty spleen”

101
Q

What type of anemia does EIA cause?

A

Cyclic nature of virus produces bouts of regen and non-reg anemia

102
Q

What types of hemolysis does EIA cause?

A

EVIV-acute form

103
Q

How does EIA produce it’s CS?

A

Anemia–> decress in erythropoiesis b/c of inflammationThrombocytopenia–> 2 to immune mediated destruction (acute)

104
Q

What cells does FeLV infect? TQ

A

Hematopoetic precursor cells–> nonregenerative anemia

105
Q

Other than anemia what else does FeLV cause?

A

Immunosuppresion–> InfectionsBonemarrow disordersLymphosarcoma

106
Q

Does FIV cause anemia?

A

Not from FIV but from concurrent dz

107
Q

What do oxidative agents do to RBC’s?

A

Heinz BodiesEV & IV hemolysis

108
Q

What are the oxydative agents in horses?

A

Red maple toxicityphnothiazine

109
Q

What are the oxidative agents of ruminants?

A

Brassica spp.Nitrite toxicity–>methemogloninemiaCopper Tox–> acute IV hemolytic anemia

110
Q

What oxidative agents for dogs?

A

Acetaminophen

111
Q

What are oxidative agents to all species?

A

Onions & garlic

112
Q

What nutritional deficiencies can cause anemia?

A

Iron–> 2 to chronic hemorrhageHypophosphatemic hemolytic anemia–>IV in post parturient cowsWater intox–> calves IV osmotic hemolysis

113
Q

What erythropoietic porphyrias cause an accumulation of porphyrin?

A

Congenital erythropoietic porphyriaBovine Erythropoietic protoporphyria

114
Q

What is congenital erythropoietic porphyria and what does it do?

A

Disorder of porphyrin synthesisRed/brown discoloration of teeth/bone/urinePhotosentitizationHemolytic anemia

115
Q

What is Bovine Erythropoietic protoporphyria and what does it cause?

A

Disorder of HEME synthetasePhotsentitization only

116
Q

Who gets Pyruvate Kinase deficiency (PK)?

A

BasejisAbyssinianSomaliDSH

117
Q

What is the consequence of of PK?

A

glycolytic enzyme= decrease in ATP–>decreased RBC fxn & lifespan–>EV hemolysis=ANEMIA

118
Q

What is the consequence of of PKK?

A

Dogs: progressive myelofiborsis, Osteosclerosis, hemo derosisCats: favorablr prognosis, NO osteosclerosis

119
Q

Who gets Phosphofructokinase defcency (PFK)?

A

English SPringer & Cocker Spaniels

120
Q

What is the consequence of of PFK?

A

glycolytic enzyme=decreased ATP, Increased fragility under alkaline conditions

121
Q

What is the consequence of of PFK?

A

NO anemia, chrinic EV hemolysis & marked reticulocytosis, hypervetilation causes alkalemia–>acute IV hemolysis

122
Q

Which (PFK or PK) gives anemia? TQ

A

PK= AnemiaPFK= No Anemia

123
Q

What causes Equine Granulocytic Erlichiosis? (EGE)

A

Intracellular BacT Anaplasma phagocytophilum

124
Q

What does EGE casue?

A

Morulae in Neut cytoplasmSeasonal Necrotizinf vasculitis

125
Q

What is Leukocyte Adhesion deficiency (LAD)?

A

Inherited fatal contitionDefeciency of B2 chain of Leuk integrin impairs migration causing Severe Neutrophilia in blood

126
Q

Who gets LAD?

A

Holstein (BLAD) and Irish Setters

127
Q

What is Chediak-Higashi Syndrome?

A

CHS inheritied by cow, persians and blue/silver fox

128
Q

What does CHS cause?

A

Decreased immunity–>neutropeniaPlatlet dysfxn –> thrombocytopenia –>bleedingOcular/cutaneous HYPO pigmentationCytoplasmic inclusions in blood cells

129
Q

What is the infectious agent of potomac horse fever?

A

Ehrlichia risticii

130
Q

What is the pathogenesis of PHF?

A

Infects monocytes & enterocytes–>diarrheal Dz

131
Q

What are the 3 main CS of Ehrlichia canis? TQ

A

ThrombocytopeniaAnemia–>non regen from bone marrow hypoplasiaLeukopenia

132
Q

What is the pathogenesis of Ehrlichia canis? TQ

A

Infects mononuclear cells & vascular endothelium –>vasculitis

133
Q

What is hemophagocytic syndrome and who gets it?

A

Cats and DogsProlif of non-neoplastic well differenciated but highly erythrophagic macrophages2 to cytokines from other dz

134
Q

What is the pathogenesis of hemophagocytic syndrome?

A

Macs in high # in BM, LN, spleen & liverCytopenia of 2 or more cell linesSplenomegaly lymphadenopathy & bleeding tendencies

135
Q

What is the eitiology of immune mediated thrombocytopenia?

A

2 to Infection, drugs, neoplasia or other IM Dz’s

136
Q

What is Evans Syndrome?

A

IMT + IMHA

137
Q

What is infectious canine cyclic thrombocytopenia?

A

Anaplasma Platys–> infects platletes and increases destruciton

138
Q

How does BVDV cause thrombocytopenic hemorrhage syndrome?

A

infects bone marrow megakaryocytes and circulating platelets impairing function.

139
Q

How does FeLV cause thrombocytopenia?

A

Infects hematopoietic cells causing thrombocytopenia & thrombocytosis, platelets are larger with less fxn. direct cytopathic effects, myelophthisis, & IM destrction

140
Q

What is the primary inherited platelet function disorder?

A

Chediak-higashi syndrome

141
Q

What is the most common canine hereditary bleeding disorder? TQ

142
Q

Does vWD cause thrombocytopenia? TQ

143
Q

What are the types of vWD?

144
Q

What is the pathogenesis of vWD?

A

Type 1: Low vWF, normal multimer proportions, mild-mod bleedingType 2: Low vWF Absence of Lrg multimers, Mod-severe bleedingType 3: Absence of vWF–>severe bleeding

145
Q

What is lymphosarcoma?

A

diverse group of malignancies arising in lymphoid tissue outside of the bone marrow

146
Q

What coagulation factors are Vit K dependant?

A

2, 7, 9, 10

147
Q

What is DIC?

A

A concumptive coagulopathy: continuous activation of both coagulation and fibrinolytic pathways

148
Q

What is the sequele of DIC?

A

Initial: hypercoagulobilities–>thrombosis & infarctionSubsequently: hypocoagulabilities–>hemorrhage

149
Q

What coagulation factors are nonfunctional in hemophilia A & B?

A

A: VIII (8)B: IX (9)

150
Q

What is the inheritance pattern of hemophilia A & B?

A

Both are X linked so carrier females are asymptomatic

Meg's (2 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2025 Bold Learning Solutions. Terms and Conditions