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Parasitology > Hemoflagellates > Flashcards

Hemoflagellates Flashcards

1
Q

Amastigote

A

Immobile
Found in humans, vertebrates
Found in tissues, Macrophages

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2
Q

Trypomastigote

A

Mobile
Found in human, vertebrates
In blood

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3
Q

Pro mastigote and epimastigote

A

Found in insect or fly

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4
Q

Leishmania has what stages

A

Promastigote, amastigote

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5
Q

T. Brucei has which stages

A

Epi, trypano mastigotes

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6
Q

T cruzi has which stages

A

A, epi, pro, trypano mastigotes

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7
Q

Insect vector and causative organism of Chagas disease/ American trypanosomiasis/ new world trypanosomiasis

A

Kissing bug(reduviid, triatomid bug), T. Cruzi

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8
Q

Causative organism and insect vector of sleeping sickness

A

T. Brucei, tsetse fly( glossina)

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9
Q

Causative organism of cutaneous leishmaniasis

A

L.tropica

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10
Q

Causative organism of visceral leishmaniasis ( kala Azar)

A

L. Donovani. L. Brasillensis

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11
Q

Mucocutaneous leishmaniasis caused by

A

L. Infantum, l. Mexicana

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12
Q

Trypanosoma brucei gambiense causes what disease

A

West & central African trypanosomiasis (good work class)
Chronic trypanomiasis

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13
Q

Trypanosoma brucei rhoadesiense causes what disease

A

East &south African trypanosomiasis
Acute trypanomiasis

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14
Q

After dissecting kissing bug which part of the stomach has what stages of mastigotes

A

Stomach- trypano. Epi
Intestine - epi, a
Rectum- epi, trypano

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15
Q

Infective stage in the humans of Chagas disease ( t. Cruzi)

A

Metacyclic trypomastigote

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16
Q

Features of amastigote

A

Found intracellularly in tissues of human host
No free flagella
Has rod like kinetoplast
Small or ovoid in shape

17
Q

Promastigote or leptomonas form features

A

Elongatedand spindle shaped
Short free flagella
No undulating membrane
Kinetoplast near the anterior end near flagellum

18
Q

Epimastigote or crithidia features

A

Elongated and spindle shaped
Free flagellum
Has undulating membrane covering only half the body
Kinetoplast is near nucleus in the center

19
Q

Trypomastigote or trypanosoma form

A

Found in bloodstream of human host and in insect vector
Undulating membrane covering entire length
Kt near posterior end(away from flagella)

20
Q

Morphology of T. Brucei

A

Is more flexible and has graceful curves
Small kt

21
Q

Morphology of T. Cruzi

A

C- shaped
Shorter in length
Larger kt

22
Q

Infective stage of Chagas disease in kissing bug

A

Trypomastigote (blood meal)

23
Q

Diagnostic stage of Chagas disease to kissing bug

A

Metacyclic trypomastigote

24
Q

Infective stage of Chagas disease to human host

A

Metacyclic trypomastigote

25
Q

Mode of transmission of metacyclic trypomastigote in T.cruzi

A

By feces& urine in open wound or scratch because (vector borne)
Through conjunctiva - vector borne

26
Q

Differentiation of metacyclic trypomastigote into amastigote after entering human bloodstream occurs in

A

Macrophages

27
Q

How does t. Cruzi multiply in which form from amastigote to?

A

Trypomastigote by binary fission

28
Q

Features of acute phase(4-8wks) in Chagas disease

A

Symptoms - fever, malaise, lymphadenopathy
IgM abs in bloodstream

29
Q

Which antibodies can be detected in chronic phase of t. Cruzi

A

IgG abs

30
Q

Clinical features of acute phase in chagas disease

A

Chagoma(painful reddish furuncle in bite site)
Romana sign( edema in upper eyelid)

31
Q

Treatment for Chagas disease

A

Nifurtimox
Benznidazole

Parasitology (1 decks)

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