Hemoflagellate Flashcards
Hemoflagellate belongs to what family
Trypanosomatidae
Morphology of Hemoflagellates
- Non-flagellated oval form
- mononucleated and is centrally located
Amastigote
Morphology of Hemoflagellates
- Flagellated stage found in the vector, rarely seen in the blood
- mononucleated and is centrally located
- fusiform-shaped
Promastigote
Morphology of Hemoflagellates
- Long, slender flagellated form and is found in arthropod vectors
- mononucleated and is centrally located
- fusiform-shaped
Epimastigote
Morphology of Hemoflagellates
- Has undulating membrane running the length of the body and is found in the vector & bloodstream of humans
- mononucleated and is centrally located
- fusiform-shaped
Trypomastigote
What phylum does hemoflagellates belong to
Phylum Euglenazoa
True or False
All morphological forms are found in the* tryponosoma cruzi* infections
True
True or False
Only the epimastigote and trypomastigote are found tryponosoma brucei infections
True
True or False
Only the amastigote and promastigote are found tryponosoma leishmania infections
True
True or False
In diagonostic stages, those found in humans include: trypomastigote ajnd/or amastigote
True
What are the two distinctly different forms of parasite under Trypanosoma
- African sleeping sickness or Afriacan trypanosomiasis
- Chaga’s disease or American trypanosomiasis
Trypanosoma multiply through
binary fission (asexual reproduction)
Diagnosis of Tryponosoma is made through
- microscopic exam of blood
- CSF
- Lymph node aspirate
- Chancre aspirate
- Microhematocrit centrifugation
- Srologic esting
- Molecular test
Trypanosoma mainly occurs in
Africa and South America
What causes African trypanosomiasis / African sleeping sickness
it affects the lymphatic system and CNS
Trypanosoma brucei complex
What are the two subspecies of T. brucei that usually causes African trypanosomiasis
- Trypanosoma brucei gambiense (salt species)
- Trypanosoma brucei rhodesiense
What is the causative agent for Chaga’s disease/ American tryopanosomiasis
highly involved with the infection of the cardiac muscle / heart tissue
Tryponosoma cruzi
Chaga’s disease/American tryopanosomiasis is characterized by
- lesions
- conjunctivitis (Romaña’s sign)
- edema of the face and legs
What vector causes African sleeping sickness
Tse Tse fly (Glossina sp.)
What are the modes of transimission of African sleeping sickness
- vector
- mother to child infection
- blood transfusion
- sexual contact
- mechanical transmission (blood sucking insects)
Through a blood meal, the vector will be able inject _ humans
Infective stage for African sleepng sickness
Metacyclic trypomastigote form of the parasite
In the bloodstream, trypomastigotes will transform into ____ in tsetse fly’s midgut
Procyclic trypomastigote
Once the procyclic trypomastigote, it transforms into ____ and multiplies in the salivary gland thru binary fission
Epimastigotes
Epimastigotes transform into ____ (infective stage)
Metacyclic trypomastigotes
