Hemoflagellate Flashcards

1
Q

Hemoflagellate belongs to what family

A

Trypanosomatidae

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2
Q

Morphology of Hemoflagellates

  • Non-flagellated oval form
  • mononucleated and is centrally located
A

Amastigote

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3
Q

Morphology of Hemoflagellates

  • Flagellated stage found in the vector, rarely seen in the blood
  • mononucleated and is centrally located
  • fusiform-shaped
A

Promastigote

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4
Q

Morphology of Hemoflagellates

  • Long, slender flagellated form and is found in arthropod vectors
  • mononucleated and is centrally located
  • fusiform-shaped
A

Epimastigote

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5
Q

Morphology of Hemoflagellates

  • Has undulating membrane running the length of the body and is found in the vector & bloodstream of humans
  • mononucleated and is centrally located
  • fusiform-shaped
A

Trypomastigote

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6
Q

What phylum does hemoflagellates belong to

A

Phylum Euglenazoa

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7
Q

True or False

All morphological forms are found in the* tryponosoma cruzi* infections

A

True

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8
Q

True or False

Only the epimastigote and trypomastigote are found tryponosoma brucei infections

A

True

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9
Q

True or False

Only the amastigote and promastigote are found tryponosoma leishmania infections

A

True

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10
Q

True or False

In diagonostic stages, those found in humans include: trypomastigote ajnd/or amastigote

A

True

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11
Q

What are the two distinctly different forms of parasite under Trypanosoma

A
  • African sleeping sickness or Afriacan trypanosomiasis
  • Chaga’s disease or American trypanosomiasis
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12
Q

Trypanosoma multiply through

A

binary fission (asexual reproduction)

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13
Q

Diagnosis of Tryponosoma is made through

A
  • microscopic exam of blood
  • CSF
  • Lymph node aspirate
  • Chancre aspirate
  • Microhematocrit centrifugation
  • Srologic esting
  • Molecular test
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14
Q

Trypanosoma mainly occurs in

A

Africa and South America

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15
Q

What causes African trypanosomiasis / African sleeping sickness

it affects the lymphatic system and CNS

A

Trypanosoma brucei complex

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16
Q

What are the two subspecies of T. brucei that usually causes African trypanosomiasis

A
  • Trypanosoma brucei gambiense (salt species)
  • Trypanosoma brucei rhodesiense
17
Q

What is the causative agent for Chaga’s disease/ American tryopanosomiasis

highly involved with the infection of the cardiac muscle / heart tissue

A

Tryponosoma cruzi

18
Q

Chaga’s disease/American tryopanosomiasis is characterized by

A
  • lesions
  • conjunctivitis (Romaña’s sign)
  • edema of the face and legs
19
Q

What vector causes African sleeping sickness

A

Tse Tse fly (Glossina sp.)

20
Q

What are the modes of transimission of African sleeping sickness

A
  • vector
  • mother to child infection
  • blood transfusion
  • sexual contact
  • mechanical transmission (blood sucking insects)
21
Q

Through a blood meal, the vector will be able inject _ humans

Infective stage for African sleepng sickness

A

Metacyclic trypomastigote form of the parasite

22
Q

In the bloodstream, trypomastigotes will transform into ____ in tsetse fly’s midgut

A

Procyclic trypomastigote

23
Q

Once the procyclic trypomastigote, it transforms into ____ and multiplies in the salivary gland thru binary fission

A

Epimastigotes

24
Q

Epimastigotes transform into ____ (infective stage)

A

Metacyclic trypomastigotes

25
Q

What is the infective stage of the Trypanosoma brucei complex to humans

A

Metacyclic trypomastigotes

26
Q

What is the infective stage of the parasite to the vector

A

Trypomastigotes in the blood

27
Q

Trypanosoma brucei rhodesiense is mostly seen in

A

East African Regions

28
Q

what is the vector for Trypanosoma brucei rhodesiense

A

Tsetse fly (glossina morsitans grp)

29
Q

primary reservoir of Trypanosoma brucei rhodesiense

A

Animals (wild or domestic pets)

30
Q

True or False

The disease caused byTrypanosoma brucei rhodesiense can be acute but severe

A

True

31
Q

Epidemiology ofTrypanosoma brucei rhodesiense

A

Anthropozoonosis

The infection is commonly attribiuted to the mechanical transmission caused by the vector tsetse fly

32
Q
A