Hemodynamics & Shock Flashcards
Define shock
A potentially fatal reaction from conditions including infection, injury, hemorrhage, dehydration or HF (a state of acute circulatory failure (heart or perfusion failure))
Cellular dysoxia (less circulation/oxygen delivery to tissues = anaerobic metabolism), causes END ORGAN DYSFUNCTION
In states of SHOCK, what happens to the BP and MAP? Provide cutoff values.
Systolic BP < 90 mmHg OR↓by 40 mmHg from baseline
MAP < 65 mmHg
What are some signs of hypoperfusion in shock?
Cold, clammy, mottled skin
Scvo2 <65% OR Svo2 <60%
Lactate >2 mmol/L
What are signs of organ dysfunction in shock?
Encephalopathy, lethargy, confusion
Liver dysfunction
Urine output <0.5 mL/kg/hr
What is the equation for calculating MAP?
1/3 SBP + 2/3 DBP
What THREE stages are included in Stroke Volume?
Preload
Intrinsic contractility
After load
What is the equation for cardiac output (CO)?
HR x SV (stroke volume)
What two hemodynamic parameters multiply to make MAP?
CO (cardiac output) x SVR (systemic vascular resistance)
What value can be obtained from a central venous catheter? What can be administered through a CVC?
Measure central venous O2 (Scvo2)
Administer:
- fluids
- vasopressors
- antimicrobials
- TPN
What is another name for pulmonary artery catheters? What can be measured? Why is it not commonly used?
aka Swan Ganz
Measures: preload, CO, Svo2, systemic vascular resistance
Not used commonly d/t major complications and high level of invasiveness
The Frank-Starling curve compares stroke volume to preload. If the patient is fluid-responsive, what does this affect?
Fluid responsive = increased cardiac output
Review: what are the GOALS in patients with shock?
MAP: > 65 mmHg
HR: < 100 BPM
CVP = 8 – 12 mmHg (uncommon)
PCWP = 12 - 15 mmHg
Cardiac Index: > 2.2 L/min/m2
Hg: 7 - 9 gm/dl
Arterial saturation: > 88-92%
SVO2 or SCVO2: > 65 % or 70 %
Lactate clearance: < 2 mmol/L
Urine output: > 0.5 ml/kg/hour
What are the four types of shock syndrome?
Hypovolemic
Distributive
Cardiogenic
Obstructive
For HYPOVOLEMIC shock, what are the changes in pulmonary capillary wedge pressure (preload), cardiac output (pump fx), systemic vascular resistance (afterload) and Svo2 (tissue perfusion)?
PCWP = decreased
CO = decreased
SVR = increased
Svo2 = decreased
(Decreased volume/preload = low CO = compensatory increase in SVR)
For CARDIOGENIC shock, what are the changes in pulmonary capillary wedge pressure (preload), cardiac output (pump fx), systemic vascular resistance (afterload) and Svo2 (tissue perfusion)?
PCWP = increased
CO = decreased
SVR = increased
Svo2 = decreased
Same volume but valve doesn’t work = increased preload pressure BUT decreased output (CO), compensatory increase in SVR