hemodynamics Flashcards
- how is the velocity of bloodflow related to the cross sectional area of a blood vessel or group of vessels?
velocity is inversely proportional to the cross-sectional area. same flow all 3 points, velocity changes. capillaries- large cross sectional area (less velocity). aorta- small cross sectional area (large velocity)
- according to ohms law, what 2 factors determine blood flow through a blood vessel.
pressure gradient and resistance.
resistance same, increase pressure gradient = incr. flow
top same, resistance increases= decrease flow.
flow directly proportional to difference in pressure gradient
- define blood pressure
force exerted by the blood against any area of the vessel wall
- what is the conversion factor from mm-Hg(mercury) to cm-H20.
1mmHg = 1.36cm H20
- what is cerebral perfusion pressure
MAP- (CVP or ICP) whichever is higher. CPP is gradient for driving flow across brain
- what is poiseulle’s law?
flow is directly proportional to pressure gradient. flow is inversely proportional to length of tube. as radius is doubled, flow increases by 16 fold.
squeeze bag or raise IV bag- increase gradient.
increase tube length= decrease flow
- according to poiseulle’s law, what factor has the greatest impact on the rate of blood flow through a vessel?
RADIUS of vessel- doubling radius of tube causes 16 fold increase in flow
- what is resistance?
impedence to blood flow in a vessel- SVR and PVR (Ohms Law)
- can resistance be measured directly
No- must be calculated- SVR and PVR
- what is the formula for calculating SVR
MAP-CVP/COx80
- what is formula for calculating PVR
MPAP-PCWP/COx80
- how would you calculate resistance when blood vessels are arranged in a series
how would you calculate resistance when vessels are arranged in parallel
they become additive- adds length, adds resistance
Rtotal= R1+R2+R3+R4…
resistance drops when you add another piece
1/Rt= 1/R1 + 1/R2 + 1/R3…
13.if you added another blood vessel in a parallel arrangement would total vascular resistance increase or decrease and why?
TVR would drop when you add another part because increase radius has profound effect, expanded cross sectional area
14.what is laminar flow?
smooth efficient flow
15.what is turbulent flow?
colliding, all over the place, inefficient flow