Hemodynamics Flashcards
Exam 2
What is Hemodynamics?
Forces that control blood flow through the body
What is the end goal of hemodynamics?
we use hemodynamics to identify and address problem to restore adequate tissue perfusion
What are compensatory mechanisms in hemodynamics?
Mechanisms that change hemodynamic forces
Think about increased heart rate, respiratory rate, and blood pressure
When do we use hemodynamic monitoring?
When compensatory mechanisms fail due to illness
What is the pathway of blood flow through the heart?
IVC/SVC -> RA -> tricuspid valve -> RV ->Pulmonic valve -> Pulmonary artery -> Lungs -> Pulmonary veins -> LA -> Mitral valve -> LV -> Aortic valve -> Aorta
What are arteries?
Strong, elastic, three-layered vessels.
Arteries dilate or constrict to meet metabolic demand.
What are capillaries?
Microscopic vessels, one cell-layer thick walls.
What are veins?
Weak, elastic, three-layered vessels with one-way valves help return blood to heart; low pressure system
What is the average amount of blood in an adult body?
5L
What do vasopressors and vasodilators act on?
Receptors in the middle muscle layer of the arteries and veins
What is the effect of vasopressors and vasodilators?
Causing contraction or expansion of arteries and veins
What does the body produce to change the diameter of arteries and veins?
Catecholamines
What is the heart?
Mechanical pump of cardiovascular system
Muscular components and one-way valves
What can cause heart failure?
Muscle or valve failure
How is muscle contraction controlled?
Electrical stimulation (ECG)
What factors affect valve function?
Pressures on the valves
What does electrical dysrhythmia cause?
Abnormal muscle contractions
What does valve dysfunction cause?
Failure of one-way flow of blood through the heart
What is valve function dependent on?
Pressure
low pressure is where you get value/pressure problems
What happens during the diastolic phase of the cardiac cycle?
Heart is at rest
Blood flows into the right and left atrium
Why are the tricuspid and mitral valves open during the diastolic phase?
Pressures in the atria and ventricles are the same
What happens during the active diastolic phase?
Atria contract and squeeze blood into the ventricles
What causes the tricuspid and mitral valves to close?
Ventricular pressure exceeds atrial pressure this is S1 and S2
What is the approximate contribution of complete atrial emptying to cardiac output?
~30% % of total cardiac output. (this is sometimes called the “atrial kick”
What defines the diastolic phase?
Ventricles at rest
What defines the systolic phase?
Ventricles working
How do high heart rates affect chamber filling?
Reduces amount of time and less pressure
What sends a signal for the ventricles to contract?
Electrical stimulation down the bundle branches and through the Purkinje fibers
What happens during the systolic phase of the cardiac cycle?
Ventricles squeeze and push blood forward through the pulmonic and aortic valves into the lungs and the aorta.
What causes the S2 heart sound?
the pressure in the arteries exceeds the pressure in the ventricles, the pulmonic and aortic valves snap shut
What is SBP?
Highest pressure in the systolic phase.
What is DBP?
Lowest pressure in the diastolic phase.
When does the heart perfuse the coronary arteries?
During the diastolic phase when the heart is at rest.
What is the formula for cardiac output?
CO = HR x SV
What factors can affect heart rate?
ANS stimulation, temperature, electrolytes, adrenal stimulation, catecholamine release
Slow HR can decrease CO…..
Slow HR can decrease CO if the body is unable to compensate with an increase in SV
Why can a fast heart rate decrease cardiac output?
The heart does not have enough time to fill with blood
What is stroke volume?
The amount of blood pumped by the heart in one beat
What factors can affect stroke volume?
Preload, afterload, and contractility
Decreased stroke volume decrease cardiac output…
Unless the body compensates with increased heart rate
What is the normal CO in adults?
4-8L
Why does a fast heart rate not give the heart enough time to fill?
Not enough time for valves to fill
What is preload?
Stretch on the ventricular myocardium at the end of diastole.
Volume and outside pressure dependent.
What is afterload?
Resistance against which the ventricle must overcome to push blood forward.
the downstream resistance that the heart must beat against.
What is contractility?
The strength of muscle contraction in the myocardium.
What effects preload?
Increased intrathoracic pressure reduces preload; High PEEP, pneumothorax, and drugs like nitroglycerine affect it. Right heart heavily depends on preload.
What increases afterload?
Stenotic valves, pulmonary hypertension, systemic hypertension, vasopressors, hypoxia, hypothermia.
What medications increase contractility?
Digoxin, Levophed, Dobutamine, Milrinone
What conditions decrease contractility?
Hypocalcemia, Hypoxia, Acidosis, Hypothermia
What are some examples of negative inotropic (weaken the force of the heartbeat) medications?
Amiodarone, Beta blockers, Calcium channel blockers, ACE inhibitors
What is Cardiac Output?
Volume of blood pumped by the left ventricle in 1 minute
What is Cardiac Index?
Volume of blood pumped by the left ventricle in 1 minute divided by body surface area
How can Cardiac Index be calculated?
CO/BSA=CI
What is the normal range for Cardiac Index?
2.5-4.2 L/min/m2
Why is Cardiac Index preferred over Cardiac Output?
Universal measurement regardless of body size
What are intracardiac pressures?
Pressures within the heart
CVP=RAP=RV diastolic during the passive diastolic phase of the cardiac cycle , RV systolic=PA systolic, PA diastolic=LAP=LV diastolic during the passive diastolic phase of the cardiac cycle, LV systolic = SBP in the aorta
intracardiac pressure
Normal Hemodynamic values for central venous pressure (CVP)
2-6 mm Hg
same as right atrium pressure
Pressure of blood in the right heart at the end of diastole. Preload of the right ventricle
Normal Hemodynamic values for pulmonary artery pressure (PAP)
15-25 mm Hg
PA diastolic=LAP=LV diastolic during the passive diastolic phase of the cardiac cycle
8-15 mm Hg
Blood pressure in the pulmonary artery. PA diastolic pressure is almost the same as PAOP, Safer than occluding PA cath.
Normal Hemodynamic values for pulmonary artery occlusive pressure (PAOP)
8-12 mm Hg
Pressure of blood in the left heart at the end of diastole. Preload of left ventricle.
What is the stroke volume amount?
60-130 mL/beat
Volume of blood ejected from LV with each heartbeat.
Normal Hemodynamic values for Systemic Vascular Resistance (SVR) (pressure in arteries) (left ventricle gov name)
770-1500 dynes/sec/m2
Resistance that LV must overcome to open aortic valve and push blood forward. Afterload of left ventricle.
Normal Hemodynamic values for Pulmonary Vascular Resistance (PVR) (right ventricle gov name)
< 250 dynes/sec/m2
Resistance that RV must overcome to open Pulmonic valve and push blood forward. Afterload of right ventricle.
Normal Hemodynamic values for Mean Arterial Pressure (MAP)
70-105 mm Hg
Average blood pressure over 1 cardiac cycle. Important for end organ perfusion
What increases as we move through the heart?
pressure
What is the normal range for ScvO2?
65%-85%
Can be drawn from the distal port of a central line or PICC line or CVP port of PA catheter.
What is the normal range for SvO2?
60%-75%
Can be drawn from distal port of PA catheter
What does a high ScvO2 or SvO2 value indicate?
Increased oxygen supply, decreased oxygen demand, or inability to extract oxygen from blood
What do low values of central venous oxygen saturation indicate?
Decreased oxygen supply or increased oxygen demand
Why is central venous oxygen saturation slightly higher?
Blood above the right atrium is measured
What does urine and EtCO2 give information on?
Cardia output
What is non-invasive hemodynamic monitoring?
Monitoring without invasive procedures
Why is cuff size important for NIBP?
To ensure accurate readings
What is the preferred measurement site for NIBP?
Upper arm
Can the forearm be used for NIBP?
Yes, but it’s less accurate
What is Jugular vein distention (JVD)?
Elevation of CVP
How is JVD measured?
Supine position with HOB at 30-45 degrees
What is lactic acid?
Byproduct of anaerobic metabolism
What does lactate measurement indicate?
Tissue perfusion
Anytime the tissues are without adequate oxygen lactic acid is produced
It is a measure of how poorly perfused the tissues are
What is the goal when trending lactate?
> 20% reduction every 2 hours until normal
What are the components of an invasive pressure monitoring system?
Invasive catheter, high-pressure noncompliant tubing, transducer with a stopcock, pressurized flush system, bedside monitor
What is the role of the transducer with a stopcock in the pressure monitoring system?
To convert the pressure into an electrical signal
What does the pressurized flush system do in the pressure monitoring system?
Maintains patency and clears any blood clots
What are invasive catheters?
Medical devices inserted into the body
Arterial lines
Central Venous Lines
Pulmonary Artery Catheters
What is high-pressure noncompliant tubing used for?
Hemodynamic monitoring
How many stopcocks should be used with high-pressure noncompliant tubing?
Less than three
Why is it recommended to minimize the number of stopcocks with high-pressure noncompliant tubing?
To reduce the risk of leaks and errors
What is a transducer?
Converts intravascular pressure into waveforms and numerical data
Why does a transducer need to be calibrated to atmospheric pressure?
To ‘zero’ the system