Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

hemo exam 7 > hemo exam 7 > Flashcards

hemo exam 7 Flashcards

1
Q

acquired vascular 1* hemostasis defects

A

vasculitis, collagen deficiency, extensive vascular injury

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

vasculitis is

A

no vasoconstriction, usually symptom of something

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

what happens with collagen deficiency

A

no collagen to trigger 1*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

what happens with vascular injury

A

burn or road rash, vessels damaged, impede vasoconstriction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

inherited 1* hemostasis defects

A

von Willebrands disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

what happens with von Willebrand’s disease?

A

its not being produced by the endothelium and factor VIII

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

most common inherited bleeding disorder of dogs

A

von Willebrand’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

1* hemostasis platelet plug hemostasis defects are caused by either

A

number(thrombocytopenia) or function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

1 bleeding disorder of dogs

A

thrombocytopenia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

causes of thrombocytopenia

A

increase destruction, increased consumption, decreased production

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

reasons for increased destruction of platelets

A

ITP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

reasons for increase consumption of platelets

A

DIC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

reasons for decreased production of platelets

A

bone marrow reasons

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

platelets plug function issues include

A

thrombopathia, thrombocytopathy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

what happens during platelet plug function defects

A

there’s no adhesion, aggregation, secretion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

what causes function defects in the platelet plug

A

drugs, DIC, uremia (platelets cannot stick)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

hereditary causes of function defects in the platelet plug

A

vWB dz, basset hound thrombopathy, epistaxis in simmental, Chediak-Hagashi, thromblasthenic thrombopathia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

how does vWB dz effect function of platelet plug

A

platelets fail to adhere to subendothelial collagen

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

clinical signs of 1* hemostasis defects

A

petechia, ecchymosis, bleeding from the MM, bleeding out after venipuncture

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

acquired secondary hemostasis defects causes

A

Vit-K deficiency,Liver disease/failure, DIC,

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

example of what can cause vit-k deficiency

A

warfrin poisoning

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

DIC can be caused by

A

2* heat stroke, viremia, endotoxemia, massive necrosis, trauma, septicemia, IV hemolysis, consumption of hemolysis factors and hemorrahage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

hereditary causes of 2* hemostasis defects

A

hemophilias, vWB dz

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

with vWB disease lack

A

von Willebrand factor and factor 8

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

clinical signs of 2* hemostasis defects

A

hematoma, bleeding into muscle, joints, and body cavity, delayed bleeding after venapuncture*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

causes of acquired fibrinolysis defects

A

liver failure, DIC

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

how does liver failure cause fibrinolysis defects

A

can’t clear FDPS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

DIC mechanism

A

2, excessive activation, consumption, excessive FDPs, organ failure, signs or both 1 and 2*

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

thromboembolic disorder

A

clot forms then travels and lodges somewhere else

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

causes of thromboembolic disorder

A

roughened endothelium, protein C deficiency, Nephrotic syndrome

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

causes of roughened endothelium

A

cardiomyopathy, HWD dogs, IVC in AIHA

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

how does protein c deficiency cause thrombolytic disorder

A

down regulated firbrinolysis( activated PC hydrolyzes plasminogen activator inhibitor)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

how does nephrotic syndrome cause thrombolytic disorder

A

loss of antithrombin III

34
Q

In house tests for bleeding disorders (4)

A

platelet estimate, platelet count, BMBT, ACT

35
Q

platelet estimate evaluates

A

1* hemostasis, platelet number

36
Q

platelet count evaluates

A

1* hemostasis, platelet number

37
Q

BMBT stands for

A

buccal mucosal bleeding time

38
Q

BMBT method

A

dab filter paper every 10 seconds until bleeding stops

39
Q

Normal BMBT in cats and dogs

A

1-3

40
Q

BMBT evaluates

A

1* hemostasis interaction of platelets and the vascular system

41
Q

best test for platelet dysfunction

A

BMBT

42
Q

ACT stands for

A

activated clotting time

43
Q

ACT method

A

fill DET tube, mix set timer, check every 5-10 minutes for clots, stop timer when clot forms

44
Q

normal ACT time dogs

A

60-90 sec

45
Q

normal ACT time cats

A

<65 seconds

46
Q

ACT evaluates

A

2* hemostasis, intrinsic and common pathways

47
Q

best in house screening test for all 2* defects

A

ACT

48
Q

PTT stands for

A

partial thromboplastin time

49
Q

PTT evaluates

A

2* hemostasis intrinsic and common pathway

50
Q

PT stands for

A

prothrombin time

51
Q

PT evaluates

A

2* hemostasis extrinsic and common pathway

52
Q

best test for Warfrin toxicity

A

PT

53
Q

How does PTT test for warfrin toxicity

A

isolation of vit K dependent factor 7

54
Q

VWF test evaluates

A

1* and 2* hemostasis VWF and VIII

55
Q

TT stands for

A

thrombrin time

56
Q

TT detects

A

decrease in fibrinogen and thrombin inhibition by FDP’s

57
Q

FDP test evaluates

A

decreases in fibrinogen thrombin inhibition by FDP

58
Q

D-Dimers is a type of

A

FDP

59
Q

D-Dimer test for

A

very specificFDP that shows up after fibrinolysis

60
Q

order of tubes

A

RT, LT, BT

61
Q

steps to venpuncture for coag studies

A

blood draw before TX, atraumatic, multiple vacutainer

62
Q

why atraumatic venipuncture

A

to avoid introduction of tissue thromboplastin

63
Q

why make blood films immediately to evaluate 1* hemostasis

A

because platelets aggregate and dissolve in old samples

64
Q

platelet count must be done within

A

4 hours

65
Q

tubes for evaluating 1* hemostasis

A

LTT, BTT

66
Q

BTT full for what test

A

VWD factor assay

67
Q

tubes for 2* hemostasis test

A

DET, BTT, RTT

68
Q

DET for evaluation of

A

intrinsic and common

69
Q

BTT for evaluation of

A

intrinsic, extrinsic, common

70
Q

RTT for evaluation of

A

liver function

71
Q

BTT test has to be run within

A

6 hours

72
Q

symptoms of marrow failure (4)

A

non-regenerative anemia, unexplained leukopenia, unexplained thrombocytopenia, abnormal/ immature cells in peripheral blood

73
Q

indications for bone marrow sampling

A

marrow failure, tumor

74
Q

types of bone marrow samplings

A

bone marrow aspirate bone marrow core biopsy

75
Q

bone marrow aspirates provides

A

cytology sample

76
Q

bone marrow core biopsy provides

A

cytology and histology sample

77
Q

syringe used for bone marrow sampling

A

12cc

78
Q

anticoag used for bone marrow sampling

A

EDTA

79
Q

preservative for histology

A

10% neutral buffered fromalin

80
Q

needles for bone marrow cytology

A

rosenthal, illinois sternal iliac

81
Q

needle used for bone marrow core biopsy

A

jamshidi

82
Q

sites for collect bone marrow sample

A

proximal humerus, proximal femur, crest and wing of ilium, sternum and dorsal ends of ribs

hemo exam 7 (1 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions