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Heme/Onc > Heme/Onc Tx > Flashcards

Heme/Onc Tx Flashcards

1
Q

AML Induction Therapy

A

3 days of an Anthracycline + 7 days of cytarabine

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2
Q

AML Consolidation Chemo

A

3-4 cycles of cytarabine high dose over 5 days in conjuction with etoposide, daunomycin or idarubicin

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3
Q

ALL Induction Therapy (Philadelphia chromosome)

A

Gleevec (imatinib)

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4
Q

ALL Induction Therapy

A

Oncovin® (vincristine), Elspar® (L-asparaginase) or Oncaspar® (peg-L-asparaginase), and an anthracycline such as Adriamycin® (doxorubicin)

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5
Q

Older Pt with ALL

A

Hyper-CVAD (cyclophosphamide, vincristine, doxorubicin, dexamethasone)

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6
Q

ALL Induction Therapy Children

A

administering three drugs: Oncovin® (vincristine), prednisone or dexamethasone, and Elspar® (L-asparaginase) or Oncaspar® (PEG-L-asparaginase).

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7
Q

CLL Early Stage (Rai 0-II; Binet A)

A

NOTHING unless high risk/symptomatic

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8
Q

CLL Symptomatic single chemotherapy agent

A

Leukeran® (chlorambucil) and Fludara® (fludarabine), Rituxan® (rituximab), Campath® (alemtuzumab), and Treanda® (bendamustine).

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9
Q

CLL Symptomatic multitherapy Tx

A

Fludara; Cytoxan; Rituxan; Mitoxantrone; Campath
Fludara plus Cytoxan (FC);
Fludara, Cytoxan, and Rituxan (FCR);
Fludara, Cytoxan and Mitoxantrone (FCM) with or without Rituxan;
Fludara, Cytoxan, and Campath (FCC)
Cytoxan, Fludara, Campath and Rituxan (CFAR)
Nipent, Cytoxan and Rituxan (PCR)

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10
Q

CLL supportive care

A 
Intravenous Immunoglobulin
cotrimoxazole----Pneumocystis carinii
valganciclovir-----Cytomegalovirus
Systemic/broad spec antibiotics----Bacterial Infections
Antifungals----PRN for fungal infections
Neulasta or Neupogen-----Neutropenia
Epogen----Anemia
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11
Q

CML Chronic phase

A

Gleevec or Tasigna

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12
Q

CML Accelerated phase (after Gleevec failure)

A

Tasigna or Sprycel

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13
Q

CML Blastic phase (after Gleevec failure)

A

Sprycel or Nilotinib

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14
Q

Anal CA Tx

A

surgery, radiation therapy, or chemotherapy

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15
Q

Anemia Tx

A

Dietary/supplements: B12, folic acid, iron, and vitamin C
Medication: vitamin B12 injections, folic acid pills, intravenous iron or oral iron pills, antibiotics, or hormones.
Blood transfusions, or surgery.

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16
Q

Barrett’s Esophagus Tx

A

Anti-reflux medication—Without dysplasia
Anti-reflux medication possibly photodynamic/laser—-Low-grade dysplasia
Esophagectomy—-High-grade dysplasia

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17
Q

Esophageal CA Stage 0-II

A

Esophagectomy

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18
Q

Esophageal CA Stage III

A

Neoadjuvant chemotherapy and radiation followed by surgery

19
Q

Esophageal CA Stage IV

A

Multiple palliative measures, chemotherapy, radiation, surgery

20
Q

Esophageal CA chemotherapy Tx

A

Fluorouracil and Mutamycin®

21
Q

Bladder CA Stage 0-I

A

Transurethral Resection (TUR); Bladder Instillation of Bacille Calmette-Guérin (BCG)

22
Q

Bladder CA Stage II-III

A

Cystectomy; Neoadjuvant Chemo+Cystectomy

23
Q

Bladder CA Stage IV

A

Palliative chemotherapy +/- surgery

24
Q

Bladder CA Chemo

A

GC: Gemzar® (gemcitabine) and cisplatin.
MVAC: methotrexate, vinblastine, doxorubicin, and cisplatin.

25
Q

Brain CA

A

Surgery and or External Beam Radiation Therapy (EBRT)

26
Q

Breast CA chemo

A

Cyclophosphamide, doxorubicin, fluorouracil, methotrexate, Taxotere
CMF: cyclophosphamide, methotrexate and fluorouracil
CAF: cyclophosphamide, doxorubicin, and fluorouracil
AC: doxorubicin and cyclophosphamide
TAC: Taxotere, doxorubicin, cyclophosphamide

27
Q

What adjuvant to Stage II-IV Breast CA can be used?

A

Taxanes (Taxotere; Taxol)

28
Q

Breast CA Adjuvant

A

Taxanes
Estrogen modulator (Tamoxifen, Aromatase inhibitors)
HER2 (Herceptin)

29
Q

Premenopausal Estrogen modulation

A

Tamoxifen

30
Q

Postmenopausal Estrogen modulation

A

Aromatase inhibitor +/- Tamoxifen

31
Q

Cervical CA Stage 0-1 Tx

A

Total hysterectomy or conization surgery

32
Q

Cervical CA Stage 2-4 Tx

A

Chemo/Radiation

33
Q

Cervical CA Chemo

A

Platinol®, 5-fluorouracil

34
Q

Colon CA Stage I-III

A

Surgery + Adjuvant Chemo

35
Q

Colon CA Stage IV

A

Chemo + Avastin

36
Q

Colon CA Chemo Adjuvant

A

FOLFOX (LV/5-fluorouracil + Eloxatin (oxaliplatin)
CAPEOX (Xeloda (capecitabine) + Eloxatin
Xeloda

37
Q

Colon CA Chemo Stage IV

A

FOLFOX (LV/5-fluorouracil + Eloxatin (oxaliplatin)
CAPEOX (Xeloda (capecitabine) + Eloxatin)
FOLFIRI (LV/5-fluorouracil + Camptosar (irinotecan)
FOLFOXIRI (LV/5-fluorouracil + Camptosar + Eloxatin

38
Q

Essential Thrombocytopenia

A

Low-dose-aspirin; Hydroxyurea

39
Q

Myelofibrosis

A 
Jakafi
Androgens
Immunomodulators
Hydroxyurea
Blood Transfusions
Splenectomy
40
Q

Polycythemia Vera

A

Phlebotomy
Low-dose-aspirin
Hydroxyurea

41
Q

Ewing Sarcoma Localized

A

Surgery, Radiation, Chemo

42
Q

Ewing Sarcoma Metastatic

A

Chemo

43
Q

Ewing Sarcoma Chemo

A

vincristine, actinomycin D, cyclophosphamide, and doxorubicin with alternating cycles of ifosfamide and etoposide

Heme/Onc (1 decks)

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