Heme Flashcards
1
Q
How would polycythemia rubra vera present?
What would you order for inv
A
Viscosity issues: HA, paresthesias, ∆ vision Cytokine issues: Pruritus, night sweats, daytime sweats Erythromelalgia Facial plethora Thrombosis: arterial, venous Hemorrhage Hb >160 M or >165 F Leukocytosis Thrombocytosis Splenomegaly Gouty arthritis & tophi
2) JAK2 mutation [positive]
Red cell mass [elevated]
EPO [normal]
2
Q
What is your approach to polycythemia?
A
Is it a primary source [PCRV, other myeloproliferative disorders]
Is it relative —> signs of hypovolemia/low plasma volume: Vomiting/diarrhea, JVP low, dry mucous membranes & cr elevated [prerenal dehydration] —> Mx IVF & see if responds
Is it from hypoxia: COPD, OSA, CO poisoning, altitude —> EPO high [but if you don’t suspect PCRV & suspect hypoxia as cause dont order EPO order CO2]
3
Q
Name all the the DOACs you know
A
Apixaban [Eliquis]
Rivaroxaban [Xarelto]
Dabigatram [Pradexa]
Edoxaban [Lixiana]
4
Q
Name LMWH
A
Dalteparin [fragmin]
Enoxaparin [lovenox]
