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HEMA > Hematopoiesis (WBC) > Flashcards

Hematopoiesis (WBC) Flashcards

1
Q

Earliest recognizable stage in granulocytic series

A

Myeloblast

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2
Q

Primary or non-specific granules

A

Promyelocyte

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3
Q

Secondary or specific granules

A

Myelocyte

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4
Q

Youngest cell in the series wherein we cannot identify a given granulocyte

A

Myelocyte

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5
Q

Last stage capable of mitosis

A

Myelocyte

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6
Q

Youngest cell no longer capable of cell division

A

Metamyelocyte (Juvenile)

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7
Q

Predominant WBC in adult BM

A

Metamyelocyte (Juvenile)

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8
Q

<50% indentation

A

Metamyelocyte (Juvenile)

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9
Q

Kidney-shaped nucleus

A

Metamyelocyte (Juvenile)

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10
Q

Youngest cell to normally appear in peripheral blooc

A

Band

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11
Q

> 50% indentation

A

Band

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12
Q

Carry proteins from secondary granules to be released into extracellular medium

A

Storage vesicles

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13
Q

ACP
Catalase
Elastase
Eosinophilic cationic protein

A

Small Lysosomal granules

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14
Q

Cyclooxygenase
Esterase
Eosinophil peroxidase
Leukotriene C4 synthase

A

Lipid Bodies

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15
Q

Order of release of neutrophil granules

A
  1. Secretory
  2. Tertiary
  3. Secondary
  4. Primary
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16
Q

N:C ratio is 4:1

A

Myeloblast

17
Q

N:C ratio is 3:1

A

Promyelocyte

18
Q

N:C ratio is 1:1

A

Myelocyte

19
Q

Very clumped chromatin

A

Band

20
Q

Densely packed chromatin

A

Segmented neutrophil

21
Q

> 6 lobes

A

Hypersegmented neutrophils

22
Q

Remain in maturation-storage phase for 7-10 days

A

Neutrophils

23
Q

Remain in maturation-storage phase for 2.5 days

A

Eosinophils

24
Q

Remain in maturation-storage phase for 12 hrs

A

Basophils

25
Q

Maturation-Storage compartment aka

A

Marrow Reserve

HEMA (3 decks)

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