HEMATOPOIESIS Flashcards
2 types of approaching hematopoiesis
- ontogeny
- phylogeny
an approach in hematopoiesis wherein it focuses on embryonic/development POV
ontogeny
an approach in hematopoiesis wherein it focuses on evolution POV
phylogeny
formation and development of all blood cells
hematopoiesis
encompasses the overall interactions of cell renewal, cellular proliferation, differentiation, morphogenesis, functional maturation, and death
hematopoiesis
where erythroid precursor is proliferating, differentiating, and nucleating - nucleus is excluded
Erythropoietic island
in what organ is the erythropoietic island found?
Bone marrow
percentage of nucleated cells in the bone marrow
5-38%
percentage of WBCs responsible for granulopoiesis
23-85%
percentage of WBCs responsible for lymphopoiesis
1-5%
platelet formation
Thrombopoiesis
precursor cell
Hemocytoblast
3 types of stem cells
- totipotential
- pluripotential
- multipotential
stem cell that is more versatile and present few hours after fertilization
totipotential stem cell
this stem cell can differentiate into any type of tissue including blood cells
totipotential stem cell
this stem cell is the source of developing cell for fetus
totipotential stem cell
this stem cell occurs several days after fertilization
pluripotential stem cell
it can develop into any tissue except fetus
pluripotential stem cell