Hematopoiesis Flashcards
granulocyte maturation sequence
myeloblast, promyelocyte, myelocyte, metamyelocyte, band cell, mature neutrophil
active bone marrow is found
ends of ,long bones and in the flat bones
pluripotent stem cell
all blood cells from the marrow arise from a single pluripotent stem cell
proteins involved in cell maturation
WBC - leukoproteins
RBC - erythropotein
platelets - thrmopoiten
granulopoiesis and productions of granulocytes in bone marrow:
Granulopoiesis is specifically the production of neutrophils, eosinophils, and basophils stimulated by leukopoietins.
which cells are granulocytes
neutrophils, eosinophils, basophils, monocytes).
white blood cells and their function
two large functional groups:
granulocytes and lymphocytes
band cell and why we may see it in neutrophil in circulation
increased numbers observed in circulation indicate infection or inflammation where the bone marrow is trying to keep up with demand but does not have production of enough neutrophils ready to meet the demands
hematopoiesis
production of blood cells
granulocytes
Have granules and are capable of phagocytosis (neutrophils, eosinophils, basophils, monocytes).
lymphocytes
Do not have granules and are involved in the immune response (lymphocytes).