Hematopoiesis

Question 1

process of blood cell production, differentiation, and development.

Answer 1

Hematopoiesis

Question 2

Hematopoietic system consists of:

Answer 2

●bone marrow
●liver
●spleen
●lymph nodes
●thymus

Question 3

proliferation and differentiation of red blood cells

Answer 3

Erthyropoiesis

Question 4

development of whute blood cells

Answer 4

Leukopoiesis

Question 5

Development of platelets

Answer 5

Thrombopoiesis

Question 6

the foundation of the adult hematopoietic system

Answer 6

Hematopoietic Stem Cells (HCSs)

Question 7

Three types of Human Stem Cells

Answer 7

1. Totipotential stem cells
2. Puripotential stem cells
3. Multipotential stem cells

Question 8

●cells present in the first few hours after an ovum is fertilized.
●versatile type and can develop into any human cell type, including development from embryo into fetus

Answer 8

Totipotential stem cells

Question 9

●cells are present several days after fertilization.
●can develop any cell type, except into a fetus

Answer 9

Pluripotential stem cells

Question 10

●cells derived from pluripotent stem cells.
●found in adults, but limited to specific types of cells to form tisues

Answer 10

Multipotential Stem Cells

Question 11

Yolk sac phase

Answer 11

Mesoblastic

Question 12

Liver phase

Answer 12

Hepatic

Question 13

Bone marrow phase

Answer 13

myeloid

Question 14

3rd week of gestation, these cells aggregate into cluster of cells known as “blood island”

Answer 14

Mesoblastic Period

Question 15

This phase occurs intravascularly, or within a developing blood vessel. it remains active until 8-12 weeks of gestation.

Answer 15

Mesoblastic period

Question 16

Arise from mesodermal cells, which initially line the cavity of the yolk sac

Answer 16

Immature cells: Primitive Erythroblasts

Question 17

Globin chains produced:

Answer 17

1. Epsilon
2. Zeta
3. Gamma

Question 18

Embryonic forms of hemoglobin:

Answer 18

1. Gower I
2. Gower II Portland

Question 19

Hepatic period begins at ______ week of gestation and remain active unril 1st lr 2nd week after birth

Answer 19

5th ans 6th

Question 20

this phase occurs extravascularly, with the liver remaining the major site during fetal life and retaining activity until 1 to 2 weeks after birth.

Answer 20

Hepatic Period

Question 21

first fully developed organ in the fetus, becomes the major site of T-cell production

Answer 21

Thymus

Question 22

kidney and spleen produce?

Answer 22

B cells

Question 23

5tt of week gestation, bone cavities begin to assume the responsibility as the mainnsite of blood cell production

Answer 23

Myeloid/Medullary Period