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Hematology > Hematopoiesis > Flashcards

Hematopoiesis Flashcards

Overview of Hematopoiesis in the bone marrow Stem cells Erythroid and Myeloid precursors Megakaryocytes Development of cells in the bone marrow Function and morphology of mature cells in the peripheral blood

1
Q

The study of blood

A

Hematology

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2
Q

Phases of development of blood cells

A

Mesoblastic
Hepatic
Medullary

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3
Q

During this period, hematopoiesis is majorly mesoblastic

A

3-5weeks

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4
Q

Organ primarily responsible for hematopoiesis during the mesoblastic phase

A

Yolk sac

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5
Q

During this period, hematopoiesis is majorly hepatic

A

4-6(8) weeks

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6
Q

These (2) organs are the sites of hematopoiesis during the hepatic phase

A

Liver, Spleen

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7
Q

During this period, hematopoiesis is mejorly medullary

A

Bone marrow

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8
Q

Phases aka extramedullary phases

A

Mesoblastic, Hepatic

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9
Q

True or False:

In the mesoblastic phase, hematopoiesis also occurs in the placenta

A

True

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10
Q

WBC and Platelets are first formed during this phase of hematopoiesis

A

Hepatic Phase

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11
Q

Active form of bone marrow

A

Red marrow

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12
Q

Yellow marrow is for the storage of which tissue?

A

adipose

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13
Q

(N) Myeloid:Erythroid ratio

A

3:1

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14
Q

Organ responsible for the storage of vitamins and minerals necessary for the formation of DNA and RNA

A

Liver

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15
Q

The largest lymphoid organ

A

Spleen

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16
Q

True or False: The spleen is a non-essential organ

A

True

17
Q

Organ responsible for the removal of damaged RBC

A

Spleen

18
Q

Site of T-cell maturation

A

Thymus

19
Q

Congenital Thymic Hypoplasia

A

D’George Syndrome

20
Q

Organ that filters lymph

A

Lymph nodes

21
Q

Cells responsible for the production of cytokines

A

Non-stromal cells

22
Q

Cells responsible for the control of cytokines

A

Stromal cells

23
Q

Math the signal to the response
Signals: Hypoxia, Infection, Antigen, Hemorrhage
Response: Inc. Platelet, Inc. Lymphocytes, Inc. WBC, Inc. RBC

A

Hypoxia: RBC
Infection: WBC
Antigen: Lymphocytes
Hemorrhage: Platelets

24
Q

Organs that produce erythropoietin

A

Liver, Kidney

25
Q

True or False: RBCs may proliferate without erythropoietin

A

True

26
Q

Nutrients necessary for the production of RBC

A

B12, Folic acid, Iron

27
Q

Match:
Neutrophils | Eosinophils | Basophils
Parasites | Inflammation | Bacteria and Fungi

A

Neut: Bacteria and fungi
Eo: Parasites
Baso: Inflammation

Hematology (5 decks)

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