Hematology I

Question 1

describe what is seen on peripheral blood smear in a patient with hemolytic anemia

Answer 1

normochromic normocytic anemia, with polychromasia (if very increased reticulocytes)

Question 2

describe what is seen in plasma/serum levels in hemolytic anemia

Answer 2

• increased unconjugated bilirubin
• increased free hemoglobin (more so in intravascular hemolysis)
• increased LDH
• decreased or absent haptoglobin
• in intravascular hemolysis only:
  
  • urine: hemosiderinuria, +/- hemoglobinuria