Hematology

Question 1

Normal WBC

Answer 1

5.000-10,000/cubic mm

Question 2

Normal Hgb (Female)

Answer 2

12.0-16.0 g/dL

Question 3

Normal Hgb (Male)

Answer 3

13.5-17.5 g/dL

Question 4

Normal Hct (Female)

Answer 4

36-46%

Question 5

Normal Hct (Male)

Answer 5

41-53%

Question 6

Hgb:Hct ratio

Answer 6

1:3

Question 7

Normal Platelet Count

Answer 7

150K-400K/cubic mm

Question 8

WBC Differential

Answer 8

• 60% neutrophils
• 25% lymphocytes
• 10%monocytes
• 2% bands
• 1-3% eosinophils
• <1% basophils

Question 9

WBC differential in 4 y/o

Answer 9

• 50% lymphocytes
• 42% neutrophils
• 5% monocytes

Question 10

Polycythemia

Answer 10

Increase in total # of RBC’s, amont of Hgb, or RBC mass in circulation

Question 11

Anisocytosis

Answer 11

Variations in size, RDW > 14.0

Question 12

Poikilocytosis

Answer 12

Variation in RBC shape

Question 13

Polychromasia

Answer 13

Increased # reticulocytes, >1.5%, bluish gray in color due to ribosomal material

Question 14

Hypochromia

Answer 14

Central pallor >1/3 the size of RBC

Question 15

Microcytosis

Answer 15

Presence of RBCs <7 micrometers

Question 16

Macrocytosis

Answer 16

Presence of RBCs >8.5 micrometers

Question 17

Acanthocyte

Answer 17

• Irregularly spiculated RBC

- Abetalipoproteinemia

Question 18

Echinocyte

Answer 18

• RBCs with short, reguar spicules

- Uremia

Question 19

Spherocyte

Answer 19

• RBC with no central pallor

- Hereditary spherocytosis

Question 20

Ovalocyte

Answer 20

• Eliptical RBC

- Sickle cell disease

Question 21

Schistocyte

Answer 21

• Fragmented, bi- or tri-polar spiculated RBC

- Disseminated Intravascular Coagulation (DIC)

Question 22

Sickle cell

Answer 22

• Bipolar spiculated RBC

- Sickle cell disease

Question 23

Stomatocyte

Answer 23

• Mouth-like deformity

- Hereditary stomatocytosis

Question 24

Target cell

Answer 24

• RBC with concentric circles

- Thalassemias

Question 25

Tear drop

Answer 25

- KUnipolar spiculated RBC | - Myelofribrosis

Question 26

Mean Corpuscular Volume (MCV)

Answer 26

Indicates size of RBC

Question 27

Microcytic

Answer 27

MCV < 80 fL

Question 28

Normocytic

Answer 28

MCV = 80-100 fL

Question 29

Macrocytic

Answer 29

MCV > 100

Question 30

Normal reticulocyte count

Answer 30

- 1% of RBC count | - 50K-60K / microliter

Question 31

Causes of RBC sickling

Answer 31

- Hypoxia (altitude or infection) - Cold - Stress - Physical exertion - Acidosis