Hematology Flashcards

1
Q
Which of the following is NOT a general tissue effect of cobalamin and folate deficiencies? (H20 C95 P701-2)
A.	Asthma
B.	Breast cancer
C.	Premature birth
D.	Psychiatric disturbances
A

The answer is A. Psychiatric disturbance is common in both folate and cobalamin deficiencies. Maternal folate deficiency has been implicated as a cause of prematurity, and both folate deficiency and cobalamin deficiency have been implicated in recurrent fetal loss and neural tube defects. Other tumors that have been associated with folate polymorphisms or status include follicular lymphoma, breast cancer, and gastric cancer.

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2
Q
Which of the following drugs present a definite risk of clinical hemolysis in patients with glucose-6- phosphate dehydrogenase deficiency? (H20 C96 P716)
A.	Cotrimoxazole
B.	Chloramphenicol
C.	Chloroquine
D.	Ciprofloxacin
A

The answer is A. Chloramphenicol presents doubtful risk. Both chloroquine and ciprofloxacin present possible risk.

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