Hematology Flashcards
ABO typing required …
Rh typing required …
FFP, Cryo
Platelets
Blood typing is …
And screening is …
Determines ABO and Rh of the patient and screens common AB’s using indirect Coombs test
Screening is mixing patient’s serum with RBC of known Ag combination
Major cross matching is …
Donor PRBC mixed with recipient serum.
It determines whether recipient has preformed Ab in serum against the donor cell.
This reduces immediate hemolytic transfusion rxn, but dose not reduce delayed transfusion rxn.
Minor cross matching is …
Recipient RBC added to donor serum to identify donor serum Abs
Blood groups -> RBC Ag -> plasma Ab
Group RBC Ag Plasma Ab
A A B
B B A
AB A/B None -> universal recipient
O None AB -> universal donor
There is one type of AB blood patient that cannot receive O plasma?
The (-) AB patient cannot receive O (-) plasma
T/F:
A+ patient who received 10U of O- RBCs can still safely receive both A- and B- RBCs?
True
One unit of platelets increases count by …
5000 - 10,000 cells/mm
Contraindications to FFP?
Volume resuscitation
Hemophilia
Cryoprecipitate is rich in …
Factor 8
vWB factor
Fibrinogen
Cryo and factor 8 used to replenish factor 8 in hemophilia
T/F
You can replenish vWBF by giving recombinant Factor 8?
False
Acute reversal of warfarin by giving …
Plasma prothrombin concentrate
The most common cause of bleeding disorder after massive transfusion is …
Dilutional Thrombocytopenia
Hypocalcemia develops after massive transfusion due too …
Citrate toxicity (citrate chelates Ca)
The risk of citrate toxicity after massive transfusion increased in …
Neonates FFP or platelets transfusion Hyperventilation Liver disease Hypothermia
