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Hemepath > Hematology > Flashcards

Hematology Flashcards

1
Q

Causes of spurious increase in WBC

A
  1. Cryoglobulins
  2. Monoclonal proteins
  3. Nucleated RBCs
  4. Platelet clumps
  5. Unlysed RBCs
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2
Q

Causes of spurious decrease in WBC

A

Clotted sample

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3
Q

Causes of spurious increase in RBC

A
  1. Cryoglobulins
  2. Macrothrombocytes
  3. Markedly high WBC count
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4
Q

Causes of spurious decrease in RBC

A
  1. Clotted sample
  2. In vitro hemolysis
  3. Microcytic or fragmented RBCs
  4. RBC agglutination
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5
Q

Causes of spurious increase in HGB

A
  1. Cyroglobulins
  2. Hyperbilirubinemia
  3. In vitro hemolysis
  4. Lipemia
  5. Monoclonal proteins
  6. Markedly high WBC count
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6
Q

Causes of spurious decrease in HGB

A

Clotted sample

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7
Q

Causes of spurious increase in HCT

A
  1. Cryoglobulins
  2. Hyperglycemia
  3. Macrothrombocytes
  4. Markedly high WBC count
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8
Q

Causes of spurious decrease in HCT

A
  1. Clotted sample
  2. In vitro hemolysis
  3. Microcytic or fragmented RBCs
  4. RBC agglutination
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9
Q

Causes of spurious increase in MCV

A
  1. Hyperglycemia
  2. Markedly high WBC count
  3. Old sample (swollen RBCs)
  4. RBC agglutination
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10
Q

Causes of spurious decrease in MCV

A
  1. Cryoglobulins
  2. In vitro hemolysis
  3. Macrothrombocytes
  4. Microcytic or fragmented RBCs
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11
Q

Causes of spurious increase in platelets

A
  1. Cyroglobulins
  2. In vitor hemolysis
  3. Fragmented WBCs
  4. Microcytic or fragmented RBCs
  5. RBC inclusions
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12
Q

Causes of spurious decrease in platelets

A
  1. Clotted sample
  2. Macrothrombocytes
  3. Platelet clumps or satellitosis
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13
Q

Associations with decreased MCV and decreased MCH

A

iron deficiency, lead poisoning, thalassemia

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14
Q

Associations with normal MCV and normal MCH

A

sudden blood loss, chronic inflammation, kidney failure, pregnancy

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15
Q

Associations with high MCV

A

vitamin B12/folate deficiency, certain drugs, MDS, hemolysis

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16
Q

Associations with decreased MCHC

A

lead poisoning, vitamin B6 deficiency, copper deficiency

17
Q

Associations with normal MCHC

A

iron deficiency

18
Q

Associations with increased MCHC

A

hereditary spherocytosis, sickle cell disease and homozygous hemoglobin C disease

19
Q

Associations with increased RDW

A

recent transfusion, iron deficiency, vitamin B12/folate deficiency, RBC fragmentation or agglutination, sideroblastic anemia, MDS

Hemepath (2 decks)

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