Hematology Flashcards
excessive vit D
raised Ca and raised PO4-
renal failure
raised PO4- and low Ca
primary hyperPTH
Ca high and PO4- low
PTH reabsorb Ca and reduce PO4- reabsorption
hypoPTH
low Ca and high PO4-
normal ALP
bone met
high Ca and PO4- normal
raised ALP
clotting cascade
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AML M3 translocation
t(15;17)
acute promyelocyte leukaemia
Auer rods seen in?
AML M3
procoagulant - DIC after treatment for AML M3
ALL demographic features
young children
asso. with Down’s syndrome
low RBC, low PLT, high WCC, blast cells+++
Auer rods absent
ALL s/s
lymphadenopathy
hepatosplenomegaly
bone pain
(same as AML)
CLL is due to?
massive overproduction of leukaemia lymphocytes
CLL has what cells?
smudge cell
Hairy cell leukaemia is what?
B cell disease
Hairy cell leukemia features
splenomegaly
pancytopenia
dry tap on BM aspiration
CML feature
Philadelphia chromosome t(9;22) leucocytosis low ALP basophilia splenomeagaly