Hematology Flashcards
True or False:
At birth, in a normal full term, they have lower hemoglobin and hematocrit and smaller RBCs.
False. Higher hemoglobin and hematocrit and bigger RBCs
True or False:
At birth, in a normal full term, they have lower hemoglobin and hematocrit and smaller RBCs.
False. Higher hemoglobin and hematocrit and bigger RBCs
True or false:
There is physiologic anemia of infancy after the first week of lofe until 6 to 8 weeks.
True
The most widespread and common nutritional disordee in the world
Iron Deficiency
True or False:
Hemoglobin falls during the first 2 - 3 months
True
Iron deficiency anemia:
Decreased serum ferritin
Decreased serum iron
Increased iron binding capacity
Serum transferrin increases (then)
Decreased transferrin
Iron deficiency anemia:
Decreased serum ferritin
Decreased serum iron
Increased iron binding capacity
Serum transferrin increases (then)
Decreased transferrin
The most important clinical sign of iron deficiency but is only evident if hemoglobin falls to 7 - 8 g/dL
Pallor
The most concerning effects in infants and adolescents are impaired intellectual and motor functions before anemia develops
Iron deficiency anemia
Microcytic anemia:
IDA
Thalassemia
Hemoglobinopathies
Microcytic anemia:
IDA
Thalassemia
Hemoglobinopathies
IDA
Decreased Ferittin
Decreased Serum Iron
Increased Total Iron Binding Capacity
IDA
Decreased Ferittin
Decreased Serum Iron
Increased Total Iron Binding Capacity
Noted increased RBCs and Normal RDW (Rbc distribution width)
Thalassemia
Daily dose of elemental iron in IDA:
3-6mg/kg of Elemental Iron in 3 Divided Doses
IDA correction, repeat CBCP during this time and will be observed to havd at least 1-2 g/dL increase in hemoglobin or has normalized already
4 weeks
Iron medication is continued until when to re establish iron stores:
8 weeks
A genetoc disorder in globin chain production with ineffective erythropoiesis
Thalassemia
The marrow is hyperactive bit there are only a few reticulocytes nd severe anemia
Thalassemia
Laboratory findings in Thalassemia:
Elevated unconjugated serum bilirubin
High ferittin and Transferrin
Causes these two clinical syndrome: episodic hemolytic anemia and chronic non-spherocytic hemolytic anemia
G6PD Deficiency
The blood may reveal precipitated hemoglobin (Heinz Bodies)
G6PD Deficiency
Hallmark of hemophilic bleeding:
Hemarthrosis
This condition is associated with hypoxia, acidosis, tissue necrosis, shock and or endothelial damage
Disseminated Intravascular Coagulopathy