Hematology Flashcards
Hematocrit
HCT or PVC; Ratio or percent of RBCs to blood. Low HCT could be indicative of anemia, vitamin deficiency or infection (due to high WBC count). High HCT could be dehydration or polycythemia vera
40-51% males
34-46% females
MCH
Mean Cell Hemoglobin (the average weight of hemoglobin in RBCs in pg). MCH = Hemoglobin/RBC
MCHC
Mean Corpuscular Hemoglobin Concentration; calculated concentration of hemoglobin in your RBCs
MCHC (g/dL)=( Hemoglobin/Hematocrit) x100
31-36 g/dL
Hemoglobin
Direct measurement of hemoglobin in your blood. Hemoglobin is from RBCs by the instrument and measured at 540nm
13-18 males, 12-16 females
RDW-SD and RDW-CV
Red cell distribution WIDTH
SD is the distribution’s peak width at 20%, and CV Is RCW-SD/ MCV
RDW-CV: 9-15%
Macrocytic
MCV is high, ie the cells are big
Hyperchromic cells
MCHC is high
Specimen type
Whole blood in EDTA 2k or 3k anticoagulant
Blue top is acceptable if EDTA platelet clumping or satelitism is noted but you must multiply the platelet count by 1.11 to adjust for the sodium citrate dilution
WBC
White blood cells
3.9-11 x10^3
RBC
Red blood cells
- 3-5.8x10^6 /ul males
- 7-5.1 females
Platelet
130-400x10^3/ul
NRBC
Nucleated red blood cells
0-2%
D-Dimer
D-Dimer = dimerization of 2 subunits of fibrin degradation products. Indicative of a blood clot breakdown
PT
Prothrombin Time - a measure of clotting efficiency (in minutes) for the extrinsic pathway and activity of oral anticoagulants such as Warfarin or Coumadin.
PTT or APTT
Partial Thromboplastin Time or Activated Partial Thromboplastin Time - a measure of clotting efficiency in minutes for the intrinsic pathway
