Hematologic Lab Profile

Question 1

RBC count reference range

Answer 1

F: 4.2-5.4 million/uL
M: 4.7-6.1 million/uL

Question 2

Hemoglobin (Hgb) reference range

Answer 2

F: 12-16 g/dL
M: 14-18 g/dL

Question 3

Hematocrit (Hct) reference range

Answer 3

F: 37-47%
M: 42-52%

Question 4

Mean corpuscular volume (MCV) reference range

Answer 4

80-95 fL

Question 5

Mean corpuscular hemoglobin (MCH) reference range

Answer 5

27-31 pg

Question 6

Mean corpuscular hemoglobin concentration (MCHC) reference range

Answer 6

32-36 g/dL

Question 7

WBC count reference range

Answer 7

5,000-10,000/mm^3

Question 8

Reticulocyte count reference range

Answer 8

0.5-2.0% of RBCs

Question 9

Total iron-binding capacity (TIBC) reference range

Answer 9

250-460 mcg/dL

Question 10

Iron (Fe) reference range

Answer 10

F: 60-160 mcg/dL
M: 80-180 mcg/dL

Question 11

Serum ferritin reference range

Answer 11

F: 10-150 ng/mL
M: 12-300 ng/mL

Question 12

Platelet count reference range

Answer 12

150,000-400,000/mm^3

Question 13

Hemoglobin electrophoresis reference range

Answer 13

Hgb A1: 95-98%
Hgb A2: 2-3%
Hgb F: 0.8-2%
Hgb S: 0%
Hgb C: 0%

Question 14

Direct Coombs’ and indirect Coombs’ test

Answer 14

Negative

Question 15

Prothrombin time (PT)

Answer 15

11-12.5 sec

Question 16

What do increased levels of RBC, Hgb, and Hct indicate?

Answer 16

Possible anemia or hemorrhage

Question 17

What do decreased levels of RBC, Hgb, and Hct indicate?

Answer 17

Possible chronic hypoxia or polycythemia vera

Question 18

What do increased levels of MCV indicate?

Answer 18

Macrocytic cells, possible anemia

Question 19

What do decreased levels of MCV indicate?

Answer 19

Microcytic cells, possible iron deficiency anemia

Question 20

What do increased levels of MCH indicate?

Answer 20

Same as MCV

Question 21

What do decreased levels of MCH indicate?

Answer 21

Same as MCV

Question 22

What do increased levels of MCHC indicate?

Answer 22

May indicate spherocytosis or anemia

Question 23

What do decreased levels of MCHC indicate?

Answer 23

May indicated iron deficiency anemia or hemoglobinopathy

Question 24

What do increased reticulocyte levels indicate?

Answer 24

Chronic blood loss

Question 25

What do decreased reticulocyte levels indicate?

Answer 25

Possible inadequate RBC production

Question 26

What do increased TIBC levels indicate?

Answer 26

Iron deficiency

Question 27

What do decreased TIBC levels indicate?

Answer 27

May indicate anemia, hemorrhage, hemolysis

Question 28

What do increased iron or serum ferritin levels indicate?

Answer 28

Iron excess, liver disorders, hemochromocytosis, megaloblastic anemia

Question 29

What do decreased iron or serum ferritin levels indicate?

Answer 29

Possible iron deficiency anemia, hemorrhage

Question 30

What do increased platelet count levels indicate?

Answer 30

Polycythemia vera or malignancy

Question 31

What do decreased platelet count levels indicate?

Answer 31

Bone marrow suppression, autoimmune disease, hypersplenism

Question 32

What do hemoglobin electrophoresis variations indicate?

Answer 32

Hemoglobinopathies

Question 33

What do positive direct and indirect Coombs’ test results indicate?

Answer 33

Antibodies to RBCs

Question 34

What does increased prothrombin time indicate?

Answer 34

Possible deficiency of clotting factors V and VII

Question 35

What does decreased prothrombin time indicate?

Answer 35

May indicated vitamin K excess