Hematologic

Question 0

What are some complications to the skeleton secondary to sickle cell anemia?

Answer 0

generalized osteoporosis, medullary infarcts, secondary salmonella/ staph osteomyelitis, vertebral body collapse,
posterior mediastinal extramedullary hematopoiesis

Question 1

The “H” shaped vertebrae is classically seen in what condition?

Answer 1

Sickle Cell Anemia
aka: fish vertebrae/step-off vertebrae
generalized osteoporosis, thin cortices, coarse trabeculae, large vascular channels, widened medullary cavity, growth deformities, epiphyseal ischemic necrosis, medullary infarcts, secondary salmonella osteomyelitis

Question 2

Which anemia tends to result in “honeycomb” trabecular patterns?

Answer 2

Thalassemia

Question 3

Hemophillic arthropathy typically occurs in which joints?

Answer 3

knee, ankle, elbow
enlarged epiphyses, widened intercondylar notch, squared inferior patella
ankle may have tibiotalar slant deformity
pseudotumors are destructive intraosseus hemorrhages, MC in femur and pelvis

Question 4

What is a common differential diagnosis when encountering hemophilic arthropathy of the knee?

Answer 4

rheumatoid arthritis

Scurvy/Rickets?

Question 5

What are some common sites for avascular necrosis/osteonecrosis?

Answer 5

Epiphyses are particularly susceptible,

HIP

Question 6

What are 5 typical causes of avascular necrosis?

Answer 6

vaso-occlusive disorders
trauma, hemoglobinopathy, Caison’s disease, corticosteroid overuse, collagen disease radiation, alcoholism, panreatitis, gout….