Hema 1 Flashcards
Process of cessation/ stopping of bleeding —> clot formation and clot dissolution
Hemostasis
Making of blood clot
prothrombin
Fibrinolytic substances
Anti-thrombic
Bleeding are stopped by
Clot formation
Unwanted/ excessive clot formation are prevented by
Body’s circulating INHIBITORS
Substance that retards to stops a process or chemical reax
Inhibitors
Blood clot that obstructs a blood vessel
Thrombus
Mass (clot) of blood or foreign matter carried in the circulation
Embolus
Coagulation
Clot formation
Process of forming FIBRIN CLOT
FIBRINOLYSIS
clot dissolution
Emzymatic breakdown of BLOOD CLOT
ARTERIOsclerosis
Abnormal thickening and hardening of walls
Causing loss of elasticity
Impaired blood circulation
ATHEROsclerosis
Form of arteriosclerosis in which LIPIDS, CALCIUM, CHOLESTEROL and OTHER SUBSTANCES deposit on the inner walls of arterioles
2 Theories involved in hematopoietic progenitor cells
- MONOPHYLETIC THEORY
- POLYPHYLETIC THEORY
Every cell lineage has its own stem cell
POLYPHYLETIC THEORY
All blood cells are derived from a single progenitor cell called PLURIPOTENTIAL HEMATOPOIETIC STEM CELL
Widely accepted theory
MONIPHYLETIC THEORY
Normal Hemostasis
Primary Hemostasis, Secondary, Fibrinolysis
Cellular Component and Plasma Proteins
2 Major Parts of Physiologic Hemostatic System
Cellular Component
Platelets
Endothelial Cells
Neutrophils
Monocytes