Hema 1

Question 1

Process of cessation/ stopping of bleeding —> clot formation and clot dissolution

Answer 1

Hemostasis

Question 2

Making of blood clot

Answer 2

prothrombin

Question 3

Fibrinolytic substances

Answer 3

Anti-thrombic

Question 4

Bleeding are stopped by

Answer 4

Clot formation

Question 5

Unwanted/ excessive clot formation are prevented by

Answer 5

Body’s circulating INHIBITORS

Question 6

Substance that retards to stops a process or chemical reax

Answer 6

Inhibitors

Question 7

Blood clot that obstructs a blood vessel

Answer 7

Thrombus

Question 8

Mass (clot) of blood or foreign matter carried in the circulation

Answer 8

Embolus

Question 9

Coagulation

Answer 9

Clot formation
Process of forming FIBRIN CLOT

Question 10

FIBRINOLYSIS

Answer 10

clot dissolution
Emzymatic breakdown of BLOOD CLOT

Question 11

ARTERIOsclerosis

Answer 11

Abnormal thickening and hardening of walls
Causing loss of elasticity
Impaired blood circulation

Question 12

ATHEROsclerosis

Answer 12

Form of arteriosclerosis in which LIPIDS, CALCIUM, CHOLESTEROL and OTHER SUBSTANCES deposit on the inner walls of arterioles

Question 13

2 Theories involved in hematopoietic progenitor cells

Answer 13

1. MONOPHYLETIC THEORY
2. POLYPHYLETIC THEORY

Question 14

Every cell lineage has its own stem cell

Answer 14

POLYPHYLETIC THEORY

Question 15

All blood cells are derived from a single progenitor cell called PLURIPOTENTIAL HEMATOPOIETIC STEM CELL

Widely accepted theory

Answer 15

MONIPHYLETIC THEORY

Question 16

Normal Hemostasis

Answer 16

Primary Hemostasis, Secondary, Fibrinolysis

Question 17

Cellular Component and Plasma Proteins

Answer 17

2 Major Parts of Physiologic Hemostatic System

Question 18

Cellular Component

Answer 18

Platelets
Endothelial Cells
Neutrophils
Monocytes

Question 19

Plasma Proteins

Answer 19

Clot formation — Coagulation
Dissolution of clots — Fibrinolysis
Naturally Occuring Serine Protease Inhibitors — Anti-coagulation

Question 20

Narrowing of the (lumen) diameter of blood vessels

Answer 20

Vasoconstriction

Question 21

The goal of Vasoconstriction

Answer 21

To decrease blood flow

Question 22

Substance in connective tissue that will activate of platelets, following platelet adhesion, aggregation and secretion

Answer 22

Sub-Endothelial Collagen

Question 23

Vasolidation

Answer 23

Increases or enlarges the hole in blood vessel

Question 24

Veins carry ____ blood from ___ to ____

Answer 24

DEOXYGENATED
Body tissues , Heart

Question 25

It is where blood exchange happens from ____ to veins

Answer 25

CAPILLARIES ARTERIES

Question 26

It carries oxygenated blood from ___ to ___

Answer 26

ARTERIES Heart , the rest of the body

Question 27

Outermost layer of the blood vessel

Answer 27

Vascular ADVENTITA

Question 28

Middle layer

Answer 28

VASCULAR MEDIA

Question 29

Innermost vascular lining Plays an important role in hemostasis

Answer 29

VASCULAR INTIMA

Question 30

Lines the vascular intima Involved in clotting process by PRODUCING and STORING clotting component

Answer 30

Endothelial Cells or Endothelium

Question 31

Majority is produced by fibroblast

Answer 31

Collagen

Question 32

Lies just beneath the endothelial cells

Answer 32

Supporting the ECS

Question 33

Internal Elastic Lamina is composed of:

Answer 33

Elastin and Collagen

Question 34

Sub Endothelial Connective Tissue

Answer 34

Veins (Collagen&Fibroblast) / Artery (Collagen, Fibroblast and Smooth Muscle Cells) — because artery is thicker than veins

Question 35

Sub-endothelial CT thick part of Vascular Intima behind the ___

Answer 35

Endothelium Cells

Question 36

Lies beneath the endothelial tissues

Answer 36

Connective Tissue Matrix

Question 37

Highly active metabolically

Answer 37

Endothelium

Question 38

It regulates the permeability of the inner vessel wall

Answer 38

Connective Tissue Matrix

Question 39

Endothelium is involved in clotting process by

Answer 39

Producing or storing clotting components

Question 40

Platelet binds to non-platelet surfaces (sub-endothelial collagen) VWF links platelet to exposed sub-endothelial collagen

Answer 40

Platelet Adhesion

Question 41

It promotes platelet adhesion

Answer 41

VWF (Von Willebrand Factor)

Question 42

VWF binds ___ via platelet glycoprotein membrane receptor (GP Ib/ IX / V)

Answer 42

Platelet

Question 43

Also known as “Giant Bernie”

Answer 43

Bernard-Soulier Syndrome (BSS)

Question 44

There is no GP Ib/IX/V platelet membrane receptor but there is giant platelet and decrease of number of platelets in circulation

Answer 44

BSS

Question 45

It is the decrease number of platelets in circulation

Answer 45

Macrothrombocytopenia

Question 46

VW Disease

Answer 46

The VWF is absent or defective