helen mason Flashcards

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1
Q

where is phosphorylation performed

A

amino acids with hhydroxyl side chains, for example serine

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2
Q

discuss the differences between the two types of endocrine hormones

A

steroid hormones require transport proteins and have a slow speed of action. bind to and activate transcription factors

peptide hormones do not need a transport protein. cause phosphorylation, which activates proteins. peptide hormones are more rapid than steroid hormones

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3
Q

discuss what type of hormone insulin is and what its receptor is called

A

insulin is a peptide hormone and its receptor is called receptor tyrosine kinase (RTK)

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4
Q

which gland produces cortisol

A

adrenal cortex gland

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5
Q

all known mitochondrial genomes code for

A

cytochrome B

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6
Q

when proteins are bing glycosylated in the ER, which molecule is the oligosaccaride transferred from

A

dolichol phosphate

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7
Q

where is Bip found and what type of chaperon is it

A

hsp70

endoplasmic reticulum

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8
Q

where are mucins glycosylated and where does this glycosylation take place

A

Golgi Apparatus

O-linked

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9
Q

the adenine nucleotide translocator is imported into the mitochondria by what proteins

A

TOM and TIM22

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10
Q

another term for Km

A

michaelis constant

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11
Q

what is the RXL recruitment site

A

a site on the cyclin A subunit, that binds to substrates

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12
Q

where is the ATP acitve site of Cdk

A

between the alpha and beta domains

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13
Q

how does the glyphosate herbicide work

A

it inhibits the EPSP synthase

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14
Q

state the name of muscle cells and describe their structure

A

myofibers are long, thin and multinucleate

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15
Q

what is the name of the cytoplasm in muscle cells

A

sarcoplasm

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16
Q

what does each myofibre cell consist of

A

many linear structures called myofibrils

17
Q

what do myofibrils consist of

A

sarcomere contractile units

18
Q

describe the structure of the thin filaments in sacromeres

A

globular actin units (G actin) forms a fiberous actin protein (F actin), two strands wrap around each other

F actin is connected to Z lines at one end and is capped at the other end by a protein to prevent degradation

tropomyosin is a filamentous protein that wraps arounf F actin

troponin is a three subunit protein placed along the thin filaments

19
Q

discuss the structure of thick myosin filaments

A

myosin protein

consists of 2 heavy chains and 4 light chains
two light chains are associated with each hevay chain

20
Q

what are the name of the receptors on the muscle membrane that bind to Ach from the the presynaptic knob

A

nicotinoc Ach receptors

21
Q

describe what type of channel the nicotinic receptor is

A

a non selective channel that allows influx of Na, K, Ca