HEENT head and neck cancer Flashcards
60 % of OP cancer is found at the
palatine
lingual tonsils
pts with HPV + will be
young patients
less likely to smoke or drink
tumors: basaloid and poorly diff
better prognosis
S/S of OP cancer
most common: swelling and sore that doesn’t heal
red/white patch in mouth = dont heal
persist sore throat
hoarseness or change in voice
difficult breathing
lump bump or mass with/without pain
pain/ hard to chew
loosening teeth
dentures don’t fit
unexplained weight loss
fatigue
blood in saliva
neck masses are found…
age?
type:
region:
80% adults > 40 y/o
80% SSC primary type
neck and head region
pt presents to your office with lump on neck. whats your next step?
step 1: CT of neck
step 2: Find needle aspiration
step 3: flexible laryngoscopy: to see the area
step 3: PET scan
What is used in PET scan
nuclear med. imaging to see metabolic processes in the body
it uses FDG (fludeoxyglucose) to indicate which tissue is increasing its uptake and metabolic
after you find out that the pt has SCC of the neck of unknown primary, what do you do?
determine HPV status with needle biopsy of neck mass
*HPV + …. > 95% most likely be primary Tonsil or Base of Tongue (BOT)
History
PE exam
Imaging - PET scan
biopsies/tonsillectomy
TNM staging system has 3 parts
primary tumor (T) - size
*(T1,2,3,4,)
regional lymph nodes (N)
*N0, 1, 2, 3
Distant Metastasis (M)
*M0, M1
nonsurgical tx options for H/N cancer?
radiation- radiation mask
chemotherapy
what is the first line treatment for oral cancer?
surgical resection
*ex: floor of mouth resection + neck dissection
*partial glossectomy
what is neck dissection and what factors play a role in it
removal of lymph nodes and tissues from neck
factors: type and extent of cancer - stage
T/F the higher the TNM stage, the worse? -
*TNM stage is a prognostic indictor
T
what is one of the strongest predictors of a 50% reduction in survival rate for head and neck cancer
cervical nodal involvement: 2/3 of SSCHN pts has
10% = metastasis
extracapsular spread (ECS) further reduces survival
other predictors for head and neck cancer
nodal burden
perineural invasion
histologic grade
extent of necrosis
+ tumor margin
1st line Tx for oropharyngeal cancer
radiation therapy +/- chemo
*most likely tonsils or BOT
if it reoccurs –> surgery
first line Tx for laryngeal and hypopharyngeal cancer in …
early stage
advanced stage
recurrent cancer
early stage: radiation +/- chemo
advanced stage : surgery (laryngectomy/ pharyngectomy)
recurrent cancer - treated with surgery