HEENT Flashcards
Diseases caused by S. pneumoniae
COMPS Conjuctivitis Otitis media Meningitis Sinusitis
Prevnar vaccine covers this
Diseases caused by H. influenzea
COMPS Conjuctivitis Otitis media Meningitis Pneumonia Sinusitis
More than 30% PCN resistant. Most cephalosporins will remain stable in the presence of beta-lactamase
Diseases that are caused by M. catarrhalis
Less common in ABRS, AOM or CAP
More than 90% PCN resistant via beta-lactamase production
Signs and symptoms of acute bacterial rhinosinusitis (ARBS)
Persistent not improving (>10 days)
Severe (fever >102, purulent nasal drainage, facial pain, >3-4 days)
Worsening or double sickening
Symptom treatment of ABRS
Saline Nasal irrigation
Intranasal corticosteroids
Antibiotic treatment for ABRS
FIRST LINE : Augementin
Or If PCN allergy: Doxycycline Or Levofloxacin if worried about DRSP Or Moxifloxacin
Substrate
A medication or substance that is metabolized By the isoenzyme, utilizing the enzyme in order to be modified so we can reach drug site of action and/or be eliminated
Example: more than 50% of all prescription medications are CYP450 3A4 substrates (sildenafil, atorvastatin, alprazolam)
Inhibitor
Blocks the activity of the iso enzyme, limiting substrate excretion, allowing increase in substrate levels, and possible risk of substrate induced toxicity
Ex: clarithromycin is a inhibitor
Inducer
Accelerates the activity of the iso enzymes so that the substrate is pushed out the exit pathway leading to a reduction in substrate
Ex: at Johns wort is inducer
Myopia
Near sighted
Presbyopia
Worsening ability to follow an object. Blurred vision for near sight/close objects. Almost all adults >40 years.
Acute open angle glaucoma
Painless, caused by gradual increase in intercranial pressure. Presentation with gradual loss of peripheral vision.
Acute closed angle glaucoma
Unilateral acute onset of pain, redness, peripheral vision loss. Acute onset of ICP.
Macular degeneration
Loss of central vision. Most common cause of older adult vision loss.
Wet or dry disease.
Atropic macular degeneration is caused by damage to central portion of the macula (fovea) which is responsible for sharpest & color vision (a lot of cones). Usually dry disease - Caused by withering of blood vessels and vision cells of choroid (vascular tissue behind eye).
No treatment for this form. Mild central vision loss presentation. Visual aids required.
Bacterial conjunctivitis
Use optic FQ - cipro, Levo, moxifloxacin