Heart Failure Swonski

Question 1

Drug Induced HF that reduce contractility

Answer 1

ABC
Antiarrhythmics (disopyramide, flecainide)
BB (atenolol, propranolol, metorpolol)
Calcium Channel Blockers (verapamil, diltiazem)

Question 2

Drug Induced HF that cardiac toxin

Answer 2

Doxorubicin, Epirubicin, Daunomycin, CYP, Bevacizumab, Blue cohosh, imatinib, lapatinib, ethanol, cocaine, amphetamines

Question 3

Drug Induced HF that increase Na and H2O retention

Answer 3

glucocorticoids, androgens, estrogens, NSAIDs/COX-2 inhibitors

Question 4

HFrEF etiology

Answer 4

IHD, dilated cardiomyopathy, valvular disease, HTN

Question 5

HFpEF etiology

Answer 5

HTN, restricted cardiomyopathy, constrictive pericarditis, pericardial. tamponade

Question 6

Compensatory Mechanisms of Body to increase CO

Answer 6

1. increased HR & contractility
2. increased preload
3. Ventricular hypertrophy

Question 7

why are compensatory mechanisms bad in hF?

Answer 7

The heart enlarges too much and increased oxygen consumption, reducing the pumping ability of the heart