Heart failure Flashcards
1
Q
Ivbradine MOA and indications
A
Selective blockade of I f channels, selective sinus node inhibitor
Indication: Symptomatic NYHA II to IV with
Reduced LVEF<35% despite maximal dose of b blockers
Sinus rhythm with resting HR>77
2
Q
Effect of EPO on chronic HF
A
Improved exercise capacity
3
Q
MOA levosimendan
A
Enhances sarcoplasmic reticulum release and reuptake of calcium- trop C calcium sensitizer. Low arrythmogenic potential only
